1-苄基-3-吡咯烷基甲烷磺酸酯合成路线 （共 7 条）
参考文献
Warner-Lambert Company
Patent: US5347017 A1, 1994 ;
反应条件
n-Bu4N+CN- in dimethyl sulfoxide T=60 - 65°C; 60 h;
参考文献
Thomas, Christoph; Orecher, Florian; Gmeiner, Peter
Synthesis, 1998 , # 10 p. 1491 - 1496
反应条件
in N,N-dimethyl-formamide T=60°C; 48 h;
参考文献
Gmeiner, Peter; Orecher, Florian; Thomas, Christoph; Weber, Klaus
Tetrahedron Letters, 1995 , vol. 36, # 3 p. 381 - 382
反应条件
1: 87 percent / tetra-n-butylammonium azide / acetonitrile / 1 h / 65 °C 2: 1.) hydrogen, 2.) pyridine, triethylamine / 1.) methanol, 4 atm, room temperature, 4 h, 2.) room temperature, 16 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 8 p. 1586 - 1590
反应条件
1: 87 percent / tetra-n-butylammonium azide / acetonitrile / 1 h / 65 °C 2: 1.) hydrogen, 2.) pyridine, triethylamine / 1.) methanol, 4 atm, room temperature, 4 h, 2.) room temperature, 16 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 8 p. 1586 - 1590
反应条件
1: NaN3 / dimethylformamide / 80 °C 2: LiAlH4 / tetrahydrofuran / 6 h / Heating 3: 77 percent / CH2Cl2 / 20 °C View Scheme
参考文献
Huang; Luedtke; Freeman; Wu; Mach
Journal of Medicinal Chemistry, 2001 , vol. 44, # 11 p. 1815 - 1826
反应条件
1: 61 percent / dimethylformamide / 48 h / 60 °C 2: conc. HCl/H2O / 4 h / 80 °C View Scheme
参考文献
Gmeiner, Peter; Orecher, Florian; Thomas, Christoph; Weber, Klaus
Tetrahedron Letters, 1995 , vol. 36, # 3 p. 381 - 382
