1: C28H25Cl2N3NiO4 With acetic anhydride; sodium carbonate in acetonitrile T=25 - 70°C; 2: 1H-imidazole With sodium hydroxide in acetonitrile T=50°C; Michael condensation; 8 h; 3: With hydrogenchloride; water in ethanol

1: C30H31N3NiO4 With acetic anhydride; sodium carbonate in acetonitrile T=25 - 70°C; 2: 1H-imidazole With sodium hydroxide in acetonitrile T=50°C; Michael condensation; 8 h; 3: With hydrogenchloride; water in ethanol

1: C28H26ClN3NiO4 With acetic anhydride; sodium carbonate in acetonitrile T=25 - 70°C; 2: 1H-imidazole With sodium hydroxide in acetonitrile T=50°C; Michael condensation; 1.83333 h; 3: With hydrogenchloride; water in ethanol

1: C28H26FN3NiO4 With acetic anhydride; sodium carbonate in acetonitrile T=25 - 70°C; 2: 1H-imidazole With sodium hydroxide in acetonitrile T=50°C; Michael condensation; 1.5 h; 3: With hydrogenchloride; water in ethanol

hydrogenchloride; potassium carbonate 1.) MeCN, 50-55 deg C; Yield given. Multistep reaction;