1: 1-methyl-pyrrolidin-2-one With lithium diisopropyl amide in tetrahydrofuran T=-78°C; 1 h; 2: methyl chloroformate in tetrahydrofuran T=20°C; 4 h;

1: 1-methyl-pyrrolidin-2-one With lithium diisopropyl amide in tetrahydrofuran; cyclohexane T=-78°C; 1 h; Inert atmosphere; 2: carbonic acid dimethyl ester in tetrahydrofuran; cyclohexane T=20°C; 4 h; Inert atmosphere;

water hydrolysis;

1: With anhydrous potassium trimethylsilanolate in tetrahydrofuran T=20°C; 2: With hydrogenchloride in tetrahydrofuran; diethyl ether 0.0833333 h;