2,7-二氮杂螺[4.4]壬烷-2-羧酸 1,1-二甲基乙酯盐酸盐合成路线 (共 1 条)
反应条件
1: in methanol T=-3 - 20°C; 0.5 h; 2: With hydrogenchloride in water pH=3 - 4; 3: With potassium carbonate in water pH=10;
参考文献
ASTRAZENECA AB
Patent: WO2007/30061 A1, 2007 ;
Location in patent: Page/Page column 90 ;
WO 2007/030061 A1