1147550-11-5合成路线 （共 743 条）
反应条件
1: ammonium thiocyanate With montmorillonite K10 clay in acetone T=20°C; 0.666667 h; 2: p-methylbenzyl bromide T=20°C; 0.05 h; Neat (no solvent)Grinding;
参考文献
Meshram; Thakur, Pramod B.; Madhu Babu; Bangade, Vikas M.
Tetrahedron Letters, 2012 , vol. 53, # 14 p. 1780 - 1785
反应条件
1: ammonium thiocyanate With bromine; triphenylphosphine in acetonitrile T=20°C; Addition; 2: 1-methyl-4-trimethylsiloxymethylbenzene in acetonitrile T=20°C; Substitution;
参考文献
Iranpoor; Firouzabadi; Shaterian
Synlett, 2000 , # 1 p. 65 - 66
反应条件
in 3-methyl-1-butanol 1 h; Heating;
参考文献
Purushothaman; Rajasekharan Pillai
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1990 , vol. 29, # 1 p. 18 - 21
反应条件
hydrogenchloride; water
参考文献
Gupta, Arun; Mishra, Pradeep; Kashaw, Sushil K.; Jatav, Varsha; Stables
European Journal of Medicinal Chemistry, 2008 , vol. 43, # 4 p. 749 - 754
反应条件
hydrazine hydrate T=130°C;
参考文献
US2710243 , ;
Journal of Organic Chemistry, , vol. 19, p. 749
参考文献
I.G.Farbenind.
Patent: DE604639 , 1932 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 21, p. 227
参考文献
I.G.Farbenind.
Patent: DE604639 , 1932 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 21, p. 227
参考文献
Wu; Waksmunski; Hoff; Fisher; Egerton; Patchett
Journal of Pharmaceutical Sciences, 1977 , vol. 66, # 8 p. 1150 - 1153
反应条件
bromine in acetic acid
参考文献
Pohloudek-Fabini,R.; Schuessler,M.
Pharmazie, 1967 , vol. 22, p. 620 - 624
反应条件
1: ammonium thiocyanate With benzoyl chloride in acetone T=20°C; 0.333333 h; Heating / reflux; 2: 5-bromopyridin-2-yl amine in acetone 0.5 h; Heating / reflux;
参考文献
MERCK PATENT GMBH
Patent: WO2009/46784 A1, 2009 ;
Location in patent: Page/Page column 49-50 ;
WO 2009/046784 A1
