2-氰基-4'-甲基联苯合成路线 （共 139 条）
反应条件
manganese; cobalt (II) bromide; triphenylphosphine; trifluoroacetic acid in pyridine; N,N-dimethyl-formamide T=50°C;
参考文献
Amatore, Muriel; Gosmini, Corinne
Angewandte Chemie - International Edition, 2008 , vol. 47, # 11 p. 2089 - 2092
反应条件
Ni(PPh3)4 Negishi-like coupling reaction;
参考文献
Lipshutz, Bruce H.; Blomgren, Peter A.
Organic Letters, 2001 , vol. 3, # 12 p. 1869 - 1871
反应条件
hydrogenchloride in tetrahydrofuran; ethylene glycol dimethyl ether
参考文献
Sanofi-Synthelabo
Patent: US6407253 B1, 2002 ;
反应条件
cesium fluoride in 1,4-dioxane
参考文献
Symyx Technologies, Inc.
Patent: US6124476 A1, 2000 ;
反应条件
potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethanol; toluene T=100°C; Suzuki cross-coupling; 5 h;
参考文献
Kristensen, Jesper; Lysen, Morten; Vedso, Per; Begtrup, Mikael
Organic Letters, 2001 , vol. 3, # 10 p. 1435 - 1437
反应条件
thionyl chloride in toluene
参考文献
G. D. Searle and Co.
Patent: US5217985 A1, 1993 ;
US 5217985 A
反应条件
triphenylphosphine in tetrahydrofuran; water; toluene
参考文献
Great Lakes Chemical Konstanz GmbH
Patent: US6121480 A1, 2000 ;
反应条件
sodium carbonate; palladium diacetate in ethanol; n-heptane; water; toluene
反应条件
sodium carbonate; palladium diacetate in para-xylene; water; dimethyl sulfoxide; toluene
反应条件
potassium phosphate; palladium diacetate in tert-butyl alcohol T=110°C; Suzuki-Miyaura coupling; 2 h;
参考文献
So, Chau Ming; Lau, Chak Po; Chan, Albert S. C.; Kwong, Fuk Yee
Journal of Organic Chemistry, 2008 , vol. 73, # 19 p. 7731 - 7734
