2-氰基-4'-甲基联苯合成路线 （共 139 条）
反应条件
C26H16Cl6N2O2Pd2; tetrabutylammomium bromide; potassium hydroxide in methanol; water T=110°C; Suzuki coupling; 0.333333 h; Microwave irradiation;
参考文献
Civicos, Jose Francisco; Alonso, Diego A.; Najera, Carmen
European Journal of Organic Chemistry, 2012 , # 19 p. 3670 - 3676
反应条件
copper(I) oxide in N,N-dimethyl-formamide T=130°C; 12 h;
参考文献
Wen, Qiaodong; Jin, Jisong; Mei, Yuncai; Lu, Ping; Wang, Yanguang
European Journal of Organic Chemistry, 2013 , # 19 p. 4032 - 4036
反应条件
oxygen; palladium on activated charcoal in xylene T=220°C;
参考文献
Synthetic Communications, , vol. 26, # 24 p. 4633 - 4639
反应条件
[PdCl2(bis(di-tert-butylphosphino)ferrocene)]; TPGS–750–M; triethylamine in water T=20°C; Inert atmosphere;
参考文献
Isley, Nicholas A.; Gallou, Fabrice; Lipshutz, Bruce H.
Journal of the American Chemical Society, 2013 , vol. 135, # 47 p. 17707 - 17710
反应条件
[PdCl2(bis(di-tert-butylphosphino)ferrocene)]; TPGS–750–M; triethylamine in water T=40°C; Inert atmosphere;
参考文献
Isley, Nicholas A.; Gallou, Fabrice; Lipshutz, Bruce H.
Journal of the American Chemical Society, 2013 , vol. 135, # 47 p. 17707 - 17710
反应条件
palladium diacetate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in toluene T=120°C; 40 h; Inert atmosphereSealed tube;
参考文献
Zhou, Chao; Li, Yaming; Lu, Yang; Zhang, Rong; Jin, Kun; Fu, Xinmei; Duan, Chunying
Chinese Journal of Chemistry, 2013 , vol. 31, # 10 p. 1269 - 1273
反应条件
pyridine; trichlorophosphate T=100°C; 3 h;
参考文献
Carini, David J.; Duncia, John V.; Aldrich, Paul E.; Chiu, Andrew T.; Johnson, Alexander L.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 8 p. 2525 - 2547
反应条件
nitrogen in ethylene glycol dimethyl ether
参考文献
US5210211 A1, ;
US 5210211 A
反应条件
sodium carbonate in methanol; water; toluene
参考文献
US5444071 A1, ;
US 5444071 A
反应条件
C16H16Cl2N2O4Pd2; tetrabutylammomium bromide; potassium carbonate in water 5 h; RefluxDarknessInert atmosphere;
参考文献
Alacid, Emilio; Najera, Carmen
Organic Letters, 2008 , vol. 10, # 21 p. 5011 - 5014
