2-氰基-4'-甲基联苯合成路线 （共 139 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride; potassium phosphate in toluene 1 h; Heating;
参考文献
Urawa, Yoshio; Naka, Hiroyuki; Miyazawa, Mamoru; Souda, Shigeru; Ogura, Katsuyuki
Journal of Organometallic Chemistry, 2002 , vol. 653, # 1-2 p. 269 - 278
反应条件
bis-triphenylphosphine-palladium(II) chloride; potassium phosphate in toluene 1 h; Heating;
参考文献
Urawa, Yoshio; Naka, Hiroyuki; Miyazawa, Mamoru; Souda, Shigeru; Ogura, Katsuyuki
Journal of Organometallic Chemistry, 2002 , vol. 653, # 1-2 p. 269 - 278
反应条件
1: 75 percent / 12 h / 100 °C 2: 62 percent / O2; 1,8-diazabicyclo[5.4.0]undec-7-ene / 6 h / 60 °C / 375.03 Torr View Scheme
参考文献
Organic Letters, , vol. 8, # 25 p. 5741 - 5744
反应条件
1: 90 percent / 4 h / 30 °C 2: 75 percent / 12 h / 100 °C 3: 62 percent / O2; 1,8-diazabicyclo[5.4.0]undec-7-ene / 6 h / 60 °C / 375.03 Torr View Scheme
参考文献
Organic Letters, , vol. 8, # 25 p. 5741 - 5744
反应条件
1: 4-(dimethylamino)picolinaldehyde N,N-dibenzylhydrazone; bis(η4-1,5-cyclooctadiene)-di-μ-methoxy-diiridium(I) / tetrahydrofuran / 24 h / 80 °C / |Inert atmosphere 2: palladium(II) dichloride bis[bis(diphenylphosphine)ferrocene]; potassium phosphate / N,N-dimethyl-formamide / 80 °C / |Inert atmosphere 3: MMPP / methanol / 0 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 77, # 21 p. 9915 - 9920
反应条件
1.1: tributoxyborane; magnesium; iodine / tetrahydrofuran / 40 °C / |Inert atmosphere 1.2: 2 h / 20 °C / |Inert atmosphere 2.1: hydrogenchloride / water 3.1: triphenyl phosphite; K3PO4*3H2O; palladium diacetate; Ipr.HCl / tert-butyl alcohol / 16 h / 80 °C / |Inert atmosphere View Scheme
参考文献
Journal of Organic Chemistry, , vol. 77, # 17 p. 7572 - 7578
反应条件
1: hydrogenchloride / water 2: triphenyl phosphite; K3PO4*3H2O; palladium diacetate; Ipr.HCl / tert-butyl alcohol / 16 h / 80 °C / |Inert atmosphere View Scheme
参考文献
Journal of Organic Chemistry, , vol. 77, # 17 p. 7572 - 7578
反应条件
1: palladium(II) dichloride bis[bis(diphenylphosphine)ferrocene]; potassium phosphate / N,N-dimethyl-formamide / 80 °C / |Inert atmosphere 2: MMPP / methanol / 0 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 77, # 21 p. 9915 - 9920
反应条件
bathophenanthroline; sodium t-butanolate T=175°C; 6 h; Inert atmosphere;
参考文献
Shirakawa, Eiji; Itoh, Ken-Ichi; Higashino, Tomohiro; Hayashi, Tamio
Journal of the American Chemical Society, 2010 , vol. 132, # 44 p. 15537 - 15539
反应条件
tetrakis(triphenylphosphine) palladium(0) in toluene Stille Cross Coupling; Reflux;
参考文献
EP2662379 A1, ;
Paragraph 0102 ;
