1.1: potassium hydroxide / N-benzyl-N,N,N-triethylammonium chloride / toluene / 48 h / 50 °C / Inert atmosphere 2.1: formic acid / 20 °C / Inert atmosphere 3.1: hydroxylamine hydrochloride; sodium acetate / acetonitrile; water / 20 °C / Inert atmosphere 4.1: pentan-1-ol / 20 h / 135 °C / Inert atmosphere 4.2: Raney Ni / 4 h / 3102.97 Torr View Scheme

1: potassium hydroxide / N-benzyl-N,N,N-triethylammonium chloride / toluene / 48 h / 50 °C / Inert atmosphere 2: formic acid / 20 °C / Inert atmosphere 3: hydroxylamine hydrochloride; sodium acetate / acetonitrile; water / 20 °C / Inert atmosphere View Scheme

1.1: potassium hydroxide / N-benzyl-N,N,N-triethylammonium chloride / toluene / 48 h / 50 °C / Inert atmosphere 2.1: formic acid / 20 °C / Inert atmosphere 3.1: hydroxylamine hydrochloride; sodium acetate / acetonitrile; water / 20 °C / Inert atmosphere 4.1: pentan-1-ol / 20 h / 135 °C / Inert atmosphere 4.2: Raney Ni / 4 h / 3102.97 Torr 5.1: sodium hydrogencarbonate / ethanol; water; pentan-1-ol / 15 h / 20 °C / Inert atmosphere 6.1: triethylamine / dichloromethane / 22.33 h / 0 - 20 °C / Inert atmosphere 7.1: trifluoroacetic acid / dichloromethane / 20 h 7.2: pH ~ 12 8.1: sodium hydroxide / ethanol; water / 1.5 h / 60 °C View Scheme

oxalic acid in tetrahydrofuran 96 h; Heating;

potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in toluene T=50°C; 48 h; Inert atmosphere;