反应条件
1: tetrahydrofuran / 2 h / 20 °C 2: 96 percent / pyridine, phosphorus oxychloride / 3 h / 100 °C 3: N-bromosuccinimide, dibenzoyl peroxide / CCl4 / 3 h / Heating 4: 1.) sodium methoxide / 1.) DMF, 25 deg C, 0.25 h, 2.) DMF, 40 deg C, 4 h 6: 89 percent / 10percent HCl / tetrahydrofuran / 4 h / 25 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 34, # 8 p. 2525 - 2547
