N-苄氧羰基-L-脯氨酸合成路线 （共 150 条）
反应条件
sodium hydroxide in 1,4-dioxane 1 h; Ambient temperature;
参考文献
Wuensch, E.; Graf, W.; Keller, O.; Keller, W.; Wersin, G.
Synthesis, 1986 , # 11 p. 958 - 960
反应条件
triethylamine in water; N,N-dimethyl-formamide 1 h; Ambient temperature;
参考文献
Kim, Sunggak; Lee, Jae In; Yi, Kyu Yang
Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 12 p. 3570 - 3575
反应条件
triethylamine in water; acetone Ambient temperature;
参考文献
Kunieda, Takehisa; Higuchi, Tsunehiko; Abe, Yoshihiro; Hirobe, Masaaki
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 6 p. 2174 - 2181
反应条件
sodium hydroxide in 1,4-dioxane 24 h; Ambient temperature;
参考文献
Wuensch, E.; Graf, W.; Keller, O.; Keller, W.; Wersin, G.
Synthesis, 1986 , # 11 p. 958 - 960
反应条件
triethylamine in water Ambient temperature;
参考文献
Azuse; Tamura; Kinomura; Okai; Kouge; Hamatsu; Koizumi
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 10 p. 3103 - 3108
反应条件
sodium chlorite; disodium hydrogenphosphate in various solvent(s) 1 h;
参考文献
Mazzini, Claudio; Sambri, Letitia; Regeling, Henk; Zwanenburg, Binne; Chittenden, Gordon J. F.
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 22 p. 3351 - 3356
反应条件
1: With tributylphosphine; triethylamine; 1,1'-azodicarbonyl-dipiperidine in 1-methyl-pyrrolidin-2-one T=20°C; Solid phase reaction; esterification; Mitsunobu reaction; 20 h; 2: With trifluoroacetic acid in dichloromethane T=20°C; Hydrolysis; 0.5 h;
参考文献
Zaragoza, Florencio; Stephensen, Henrik
Tetrahedron Letters, 2000 , vol. 41, # 12 p. 2015 - 2017
反应条件
1: 81 percent / Et3N / tetrahydrofuran / 17 h / 20 °C 2: 76 percent / H2; 1,4-diazabicyclo[2.2.2]octane / Pd/C-ethylenediamine / methanol / 6 h / 20 °C / 760 Torr View Scheme
参考文献
Tetrahedron, , vol. 56, # 43 p. 8433 - 8441
反应条件
1: 81 percent / Et3N / tetrahydrofuran / 17 h / 20 °C 2: 76 percent / H2; 1,4-diazabicyclo[2.2.2]octane / Pd/C-ethylenediamine / methanol / 6 h / 20 °C / 760 Torr View Scheme
参考文献
Tetrahedron, , vol. 56, # 43 p. 8433 - 8441
反应条件
1: 90 percent / Et3N / acetonitrile / 2 h / 5 °C 2: 86 percent / Et3N / H2O / Ambient temperature View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 62, # 10 p. 3103 - 3108
