N-苄氧羰基-L-脯氨酸合成路线 （共 150 条）
反应条件
sodium hydrogencarbonate
参考文献
Gardiner, John M.; Bruce, Sarah E.
Tetrahedron Letters, 1998 , vol. 39, # 9 p. 1029 - 1032
反应条件
1: 65 percent / LiN3 / dimethylformamide / 168 h / Ambient temperature 2: 77 percent / DIBAL / light petroleum; toluene; hexane / 1 h / -78 °C 3: 62.5 percent / H2 / 10percent Pd/C / methanol / 6 h / 760 Torr 4: 65 percent / NaHCO3 / aq. ethanol 5: 90 percent / 80percent aq. AcOH / 120 h / Ambient temperature 6: 80 percent / aq. NaIO4 / methanol / 2 h 7: 90.5 percent / aq. NaClO2, Na2HPO4 / various solvent(s) / 1 h View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 22 p. 3351 - 3356
反应条件
1: 62.5 percent / H2 / 10percent Pd/C / methanol / 6 h / 760 Torr 2: 65 percent / NaHCO3 / aq. ethanol 3: 90 percent / 80percent aq. AcOH / 120 h / Ambient temperature 4: 80 percent / aq. NaIO4 / methanol / 2 h 5: 90.5 percent / aq. NaClO2, Na2HPO4 / various solvent(s) / 1 h View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 22 p. 3351 - 3356
反应条件
1: 77 percent / DIBAL / light petroleum; toluene; hexane / 1 h / -78 °C 2: 62.5 percent / H2 / 10percent Pd/C / methanol / 6 h / 760 Torr 3: 65 percent / NaHCO3 / aq. ethanol 4: 90 percent / 80percent aq. AcOH / 120 h / Ambient temperature 5: 80 percent / aq. NaIO4 / methanol / 2 h 6: 90.5 percent / aq. NaClO2, Na2HPO4 / various solvent(s) / 1 h View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 22 p. 3351 - 3356
反应条件
sodium hydrogencarbonate; sodium carbonate in water; acetonitrile T=50°C; Substitution; pH=9.5; 1 h;
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 43, # 5 p. 449 - 461
反应条件
triethylsilane; trifluoroacetic acid in dichloromethane 0.416667 h; Ambient temperature;
参考文献
Mehta, Anita; Jaouhari, Rabih; Benson, Timothy J.; Douglas, Kenneth T.
Tetrahedron Letters, 1992 , vol. 33, # 37 p. 5441 - 5444
反应条件
1: 98 percent / K2CO3 / dimethylformamide / 20 °C 2: 46 percent / Candida antarctica lipase / aq. phosphate buffer / 38 h / 30 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 14, # 10 p. 1323 - 1333
反应条件
1: 53 percent / 8 h / Ambient temperature 2: 83 percent / aq. NaOH / dioxane / 1 h / Ambient temperature View Scheme
参考文献
Synthesis, , # 11 p. 958 - 960
反应条件
1: thionyl chloride / 4 h / |Reflux 2: sodium hydroxide / tetrahydrofuran / 0 - 20 °C View Scheme
参考文献
Beilstein Journal of Organic Chemistry, , vol. 9, p. 633 - 640
反应条件
1: 65 percent / NaHCO3 / aq. ethanol 2: 90 percent / 80percent aq. AcOH / 120 h / Ambient temperature 3: 80 percent / aq. NaIO4 / methanol / 2 h 4: 90.5 percent / aq. NaClO2, Na2HPO4 / various solvent(s) / 1 h View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 22 p. 3351 - 3356
