3-(4-溴苯基)-N-(4-碘苯基)-3-氧代丙酰胺合成路线 （共 2 条）
反应条件
trifluoroacetic acid in N,N-dimethyl-formamide
T=60°C; 4 - 4.5 h; Product distribution / selectivity;
参考文献
MERCK and CO., INC.
Patent: WO2009/54887 A1, 2009 ;
Location in patent: Page/Page column 54-55 ;
反应条件
1: 2,2-Dimethyl-[1,3]dioxane-4,6-dione; 4-bromo-benzoyl chloride With 4-(N,N-dimethlyamino)pyridine in acetonitrile
T=0 - 20°C;
2: para-amino-iodo-benzene With trifluoroacetic acid in acetonitrile
T=40 - 70°C;
参考文献
MERCK and CO., INC.
Patent: WO2009/54887 A1, 2009 ;
Location in patent: Page/Page column 27 ;
