4-氯-6-(1H咪唑-1-基)嘧啶合成路线 (共 3 条)
反应条件
in water; N,N-dimethyl-formamide
反应条件
in tetrahydrofuran 48 h; Reflux;
参考文献
WO2012/50237 A1, ;
Page/Page column 110-111 ;
反应条件
sodium hydride 1.) THF, RT, 20 min, 2.) THF, RT, overnight; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 44, # 9 p. 1700 - 1706