4-((E)-苯乙烯基)-苯甲酸甲酯合成路线 （共 45 条）
反应条件
1: H2 / 5percent Pd/C / ethanol; ethyl acetate / 0.67 h / 20 °C / 1875.19 Torr 2: aq. NaOH / methanol / 15 h / 20 °C View Scheme
参考文献
Shinkai; Ito; Iida; Kitao; Yamada; Uchida
Journal of Medicinal Chemistry, 2000 , vol. 43, # 24 p. 4667 - 4677
反应条件
1: 90 percent / LAH / tetrahydrofuran 2: 75 percent / PPh3; DIAD 3: 90 percent / hydrazine / ethanol / Heating View Scheme
参考文献
Yang, Jye-Shane; Lin, Yan-Duo; Chang, Ya-Ho; Wang, Shin-Shin
Journal of Organic Chemistry, 2005 , vol. 70, # 15 p. 6066 - 6073
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
参考文献
Journal of Organic Chemistry, , vol. 70, # 15 p. 6066 - 6073
反应条件
1: 90 percent / LAH / tetrahydrofuran 2: 90 percent / thionyl chloride / CH2Cl2 / Heating View Scheme
参考文献
Yang, Jye-Shane; Lin, Yan-Duo; Chang, Ya-Ho; Wang, Shin-Shin
Journal of Organic Chemistry, 2005 , vol. 70, # 15 p. 6066 - 6073
反应条件
triethylamine in water; N,N-dimethyl-formamide
T=90°C; Heck Reaction; 21 h;
参考文献
Pavia, Cinzia; Giacalone, Francesco; Bivona, Lucia Anna; Salvo, Anna Maria Pia; Petrucci, Chiara; Strappaveccia, Giacomo; Vaccaro, Luigi; Aprile, Carmela; Gruttadauria, Michelangelo
Journal of Molecular Catalysis A: Chemical, 2014 , vol. 387, p. 57 - 62
反应条件
(3aS,7aS)-1,3-di-o-tolyl-octahydro-benzoimidazole-2-thione; potassium carbonate; PdI2 in water; isopropyl alcohol
T=80°C; Suzuki reaction; 5 h;
参考文献
Mingji, Dai; Liang, Bo; Wang, Cuihua; You, Zejin; Xiang, Jing; Dong, Guangbin; Chen, Jiahua; Yang, Zhen
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 13-15 p. 1669 - 1673
反应条件
tributyl-amine; silica-supported bidentate arsine palladium(0); triphenylphosphine in para-xylene
T=140°C; Heck arylation; 12 h;
参考文献
Park, Cheon Min; Kwon, Min Serk; Park, Jaiwook
Synthesis, 2006 , # 22 p. 3790 - 3794
反应条件
copper(l) iodide; tris(triphenylphosphine)ruthenium(II) chloride; zinc in 1,4-dioxane; water
T=100°C; 36 h; Schlenk techniqueInert atmosphere; chemoselective reaction;
参考文献
Schabel, Tobias; Belger, Christian; Plietker, Bernd
Organic Letters, 2013 , vol. 15, # 11 p. 2858 - 2861
反应条件
[{RhCl(C2H4)2}2] in o-xylene
Mizoroki-Heck reaction; 24 h; Heating;
参考文献
Sugihara, Toru; Satoh, Tetsuya; Miura, Masahiro; Nomura, Masakatsu
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 13-15 p. 1765 - 1772
反应条件
1: [Ph2I]BF4; polymer bound styrene With P(o-CH3C6H4); sodium hydrogencarbonate; tris(dibenzylideneacetone)dipalladium(0) chloroform complex in N,N-dimethyl-formamide
T=40°C; Arylation; 20 h;
2: sodium methylate in tetrahydrofuran; methanol
transesterification; 20 h; Heating;
参考文献
Kang, Suk-Ku; Yoon, Seok-Keun; Lim, Kwon-Ho; Son, Hoe-Joo; Baik, Tae-Gon
Synthetic Communications, 1998 , vol. 28, # 19 p. 3645 - 3655
