反应条件
1: 1.) 4-methylmorpholine, ethylchloroformate, 2.) 4-methylmorpholine / 1.) EtOAc, -15 deg C, 15 min, 2.) a.) -15 deg C, 1 h, b.) RT, 12 h 2: 1.) 10percent Pd/C / 1.) cyclohexene, MeOH, reflux, 5 h, 2.) MeOH, from 62 to 65 deg C, 110 h 3: 86 percent / LAH / tetrahydrofuran / 72 h / 60 - 65 °C View Scheme
参考文献
Falorni, Massimo; Giacomelli, Giampaolo; Lardicci, Luciano
Gazzetta Chimica Italiana, 1990 , vol. 120, p. 765 - 769
