1: 99 percent / K2CO3 / methanol / 4 h 2: 99 percent / Et3N / 0.17 h / 0 °C 3: 46 percent / K2CO3 / 18-crown-6 / dimethylformamide / 18 h / 75 °C 4: 92 percent / Pd(OH)2, cyclohexene / ethanol / 6 h / 80 °C 5: 95 percent / 2 N HCl / methanol / 18 h View Scheme

With  dichloro bis(acetonitrile) palladium(II); p-benozquinone in  tetrahydrofuran 14 h;  Heating;