(1-氧代-3-吡啶基)甲基乙酸酯合成路线 （共 9 条）
反应条件
3-chloro-benzenecarboperoxoic acid in chloroform 2 h; Ambient temperature;
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 35, # 10 p. 4068 - 4077
反应条件
in chloroform Ambient temperature;
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 35, # 10 p. 4068 - 4077
反应条件
1: 6.1 g / 1.5 h / 60 °C 2: 80 percent / m-chloroperbenzoic acid (m-CPBA) / CHCl3 / 2 h / Ambient temperature View Scheme
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 35, # 10 p. 4068 - 4077
反应条件
dimethyl sulfate 1) 60-70 deg C, 2 h, 2) 2-propanol, H2O, ice-salt cooling, 30 min, then rt, 1 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Ashimori; Ono; Uchida; Ohtaki; Fukaya; Watanabe; Yokoyama
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2446 - 2458
反应条件
dimethyl sulfate 1) 60-70 deg C, 2 h, 2) 2-propanol, H2O, ice-salt cooling, 30 min, then rt, 1 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Ashimori; Ono; Uchida; Ohtaki; Fukaya; Watanabe; Yokoyama
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2446 - 2458
反应条件
1: 1) p-nitrobenzoyl chloride, 2) AgNO3 / 1) CHCl3, -7 to -5 deg C, 2) -10 to 55 deg C 2: 30 percent / PCl3 / CHCl3 / Ambient temperature 3: 60 percent View Scheme
参考文献
Ashimori; Ono; Uchida; Ohtaki; Fukaya; Watanabe; Yokoyama
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2446 - 2458
反应条件
1: benzoyl chloride / H2O; CHCl3 / 7 h / 4 °C 2: 53 percent / K2CO3 / methanol / 2.5 h 3: 76 percent / DMSO, N,N'-dicyclohexylcarbodiimide, H3PO4 / 1.5 h / Ambient temperature View Scheme
参考文献
Ashimori; Ono; Uchida; Ohtaki; Fukaya; Watanabe; Yokoyama
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2446 - 2458
反应条件
1: 1) p-nitrobenzoyl chloride, 2) AgNO3 / 1) CHCl3, -7 to -5 deg C, 2) -10 to 55 deg C
2: 30 percent / PCl3 / CHCl3 / Ambient temperature
3: 60 percent
4: 71 percent / DMSO, N,N'-dicyclohexylcarbodiimide, H3PO4 / 1.5 h / Ambient temperature
View Scheme
参考文献
Ashimori; Ono; Uchida; Ohtaki; Fukaya; Watanabe; Yokoyama
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2446 - 2458
反应条件
1: benzoyl chloride / H2O; CHCl3 / 7 h / 4 °C
2: 53 percent / K2CO3 / methanol / 2.5 h
View Scheme
参考文献
Ashimori; Ono; Uchida; Ohtaki; Fukaya; Watanabe; Yokoyama
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2446 - 2458
