1: 97 percent / trifluoromethanesulfonic acid / CH2Cl2 / 24 h 2: 88 percent / lithium aluminum hydride / tetrahydrofuran / 1 h / Heating View Scheme

Multi-step reaction with 7 steps 1: 66 percent / bis(benzonitrile)palladium(II) chloride, air / 2-methyl-propan-2-ol / 116 °C2: 100 percent / aluminum isopropoxide / propan-2-ol / Heating3: pyridine / 15 h / 20 °C4: tetrakis(triphenylphosphine)palladium(0) / tetrahydrofuran / 24 h / 100 °C5: trifluoroacetic acid / CH2Cl2 / 0.5 h6: 99 percent / N-methylmorpholine, osmium tetraoxide / tetrahydrofuran; H2O / 24 h / 20 °C7: 1.) methyl sulfide, N-chlorosuccinimide, 2.) triethylamine / 1.) dichloromethane, -40 deg C, 1 h, 2.) from -40 to 20 deg C, 1.5 h