4-碘-2,5-二甲基苯酚合成路线 (共 4 条)
反应条件
iodine; sodium nitrite in methanol; water T=20°C; 6 h;
参考文献
Synthesis, , # 15 art. no. F03408SS, p. 2327 - 2332
反应条件
potassium iodide; benzyltriphenylphosphonium peroxymonosulfate in acetonitrile T=20°C; 2 h;
参考文献
Journal of Chemical Research, , # 4 p. 294 - 295
反应条件
iodine in aq. buffer pH=Ca. 9;
参考文献
Russian Journal of Applied Chemistry, , vol. 85, # 9 p. 1355 - 1365
Russ. J. Appl. Chem, , vol. 85, # 9 p. 1355 - 1365,11
反应条件
1: 4-iodo-2,5-dimethyl-phenol With potassium hydroxide in acetonitrile
T=60°C; 2 h;
2: 2-bromoethyl n-butyl ether With potassium iodide in acetonitrile
3 h;
参考文献
Lund, Birgitte W.; Knapp, Anne Eeg; Piu, Fabrice; Gauthier, Natalie K.; Begtrup, Mikael; Hacksell, Uli; Olsson, Roger
Journal of Medicinal Chemistry, 2009 , vol. 52, # 6 p. 1540 - 1545