2-甲基-3-丁烯-2-醇合成路线 （共 471 条）
反应条件
acetic anhydride T=80°C; 15 h; other substrates; Mechanism;
参考文献
Tetrahedron Letters, , vol. 32, # 47 p. 6965 - 6968
参考文献
Journal of the American Chemical Society, , vol. 73, p. 780
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , p. 623,627136,138
Chem.Abstr., , p. 3920
反应条件
1: 1,1-dimethylallyl alcohol With α-cyclohexylcyclohexanemethanamine; tetrabutylammomium bromide in N,N-dimethyl acetamide; water T=20°C; Heck reaction; 0.25 h; 2: 2-iodo aniline With 4'-hydroxyacetophenone oxime palladacycle catalyst in N,N-dimethyl acetamide; water T=120°C; Heck reaction; 8 h; Further stages.;
参考文献
Advanced Synthesis and Catalysis, , vol. 349, # 17-18 p. 2572 - 2584
反应条件
1: NaH / tetrahydrofuran; diethyl ether / 1.) 1 h, 2.) -5 to 5 deg C, 1 h 2: toluene / 1 h / Heating 3: 3 N KOH / dimethylformamide / 4 h / Ambient temperature View Scheme
参考文献
Jordis, Ulrich; Grohmann, Franz; Kueenburg, Bernhard
Organic Preparations and Procedures International, 1997 , vol. 29, # 5 p. 549 - 560
反应条件
trifluoroacetic acid in nitromethane T=0°C; 1.5 h; Yield given. Further byproducts given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Badet,B.; Julia,M.; Mallet,J.M.
Tetrahedron, 1988 , vol. 44, p. 2913
反应条件
1: TFA / nitromethane / 1.5 h / 0 °C 2: POCl3 / pyridine / 15 h / Ambient temperature View Scheme
参考文献
Badet,B.; Julia,M.; Mallet,J.M.
Tetrahedron, 1988 , vol. 44, p. 2913
反应条件
sodium hydride in diethyl ether
参考文献
Bertrand, M.; Waegell, B.; Zahra, J. P.
Bulletin de la Societe Chimique de France, 1991 , # 6 p. 904 - 910
反应条件
tert.-butylhydroperoxide; Rhodium trichloride T=25°C; 48 h; Yield given. Further byproducts given. Yields of byproduct given;
参考文献
Derdar, Fatma; Martin, Jacques; Martin, Claudine; Bregeault, Jean-Marie; Mercier, Jacqueline
Journal of Organometallic Chemistry, 1988 , vol. 338, p. C21 - C26
反应条件
hydrogenchloride; copper(l) chloride
参考文献
Nagai,K. et al.
Bulletin of the Chemical Society of Japan, 1978 , vol. 51, p. 3273 - 3276
反应条件
tert.-butylhydroperoxide; Rhodium trichloride T=25°C; 48 h; oxidation; effect of other reagents, solvents, reaction time and temperature; Product distribution;
参考文献
Derdar, Fatma; Martin, Jacques; Martin, Claudine; Bregeault, Jean-Marie; Mercier, Jacqueline
Journal of Organometallic Chemistry, 1988 , vol. 338, p. C21 - C26
