2-甲基-3-丁烯-2-醇合成路线 （共 471 条）
反应条件
1: 1. sodium hydride / 1. 1 h; 2. overnight
2: 53 percent / sodium / decane / 24 h / Heating
View Scheme
参考文献
Tzeng, Dongjaw; Weber, William P.
Journal of Organic Chemistry, 1981 , vol. 46, # 2 p. 265 - 267
反应条件
boron trifluoride diethyl etherate
T=45 - 50°C; Further byproducts given;
参考文献
Roy, D; Khanna, R. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 7 p. 583 - 586
反应条件
boron trifluoride diethyl etherate
T=45 - 50°C;
参考文献
Roy, D; Khanna, R. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 7 p. 583 - 586
反应条件
hydrogenchloride; zinc(II) chloride
2.) ether, CH2Cl2, -78 deg C, 24 h; Yield given. Multistep reaction. Title compound not separated from byproducts;
参考文献
Mayr, Herbert; Klein, Herbert; Sippel, Elfriede
Chemische Berichte, 1983 , vol. 116, # 11 p. 3624 - 3630
反应条件
formic acid in water
T=50 - 55°C; 2.5 h;
参考文献
Uchiyama, M.; Overeem, J. C.
Recueil: Journal of the Royal Netherlands Chemical Society, 1981 , vol. 100, # 11 p. 408 - 410
反应条件
1: 14.8 g / formic acid / H2O / 2.5 h / 50 - 55 °C
2: Jones reagent / acetone
View Scheme
参考文献
Uchiyama, M.; Overeem, J. C.
Recueil: Journal of the Royal Netherlands Chemical Society, 1981 , vol. 100, # 11 p. 408 - 410
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
T=80°C; 24 h; Inert atmosphere;
参考文献
Tsukamoto, Hirokazu; Uchiyama, Tomomi; Suzuki, Takamichi; Kondo, Yoshinori
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 16 p. 3005 - 3013
反应条件
1: pyridine; petroleum ether; phosphorus (III)-bromide
2: ethanol
3: 150 °C
View Scheme
参考文献
Crombie et al.
Journal of the Chemical Society, 1957 , p. 2754,2759
参考文献
Claisen
Journal fuer Praktische Chemie (Leipzig), 1922 , vol. <2> 105, p. 72
Chemische Berichte, 1925 , vol. 58, p. 279 Anm. 15
反应条件
boron trifluoride diethyl etherate in 1,4-dioxane
T=85°C; 4 h;
参考文献
Ramachandra, Marellapudi S.; Subbaraju, Gottumukkala V.
Synthetic Communications, 2006 , vol. 36, # 24 p. 3723 - 3727
