2-甲基-3-丁烯-2-醇合成路线 （共 471 条）
反应条件
potassium carbonate
1.) 45 min, RT 2.) methanol, water, RT; Yield given. Multistep reaction;
参考文献
Babin, Didier; Fourneron, Jean-Dominique; Julia, Marc
Bulletin de la Societe Chimique de France, 1980 , vol. 2, # 11-12 p. 588 - 600
反应条件
pentacarbonylmanganese bromide in dichloromethane
T=20°C; 2 h;
参考文献
Scott, Colleen N.; Wilcox, Craig S.
Journal of Organic Chemistry, 2010 , vol. 75, # 1 p. 253 - 256
参考文献
United Gas Improv.Co.
Patent: US2382031 , 1942 ;
反应条件
1: 46 percent / orthophosphoric acid (85percent) / petroleum ether / 35 - 40 °C
2: 70 percent / DDQ / benzene / Heating
View Scheme
参考文献
Ahluwalia, V. K.; Arora, K. K.; Mukherjee, Keya
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 12 p. 1291 - 1292
反应条件
T=50°C; 24 h; Overall yield = 27 percent; regioselective reaction;
参考文献
Trillo, Paz; Baeza, Alejandro; Najera, Carmen
Journal of Organic Chemistry, 2012 , vol. 77, # 17 p. 7344 - 7354
反应条件
1: (i) BF3*Et2O, dioxane, (ii) Ag2O, Et2O
2: (i) SnCl2, aq. HCl, dioxane, (ii) ZnCl2
View Scheme
参考文献
Burnett,A.R.; Thomson,R.H.
Journal of the Chemical Society [Section] C: Organic, 1968 , p. 850 - 853
反应条件
trifluoroacetic acid in nitromethane
T=0°C; 90 h;
参考文献
Julia, M.; Schmitz, C.
Tetrahedron, 1986 , vol. 42, # 9 p. 2485 - 2490
反应条件
in pentane
Irradiation; Product distribution;
参考文献
Sobery, Warunee; DeLuca, Joann P.
Tetrahedron Letters, 1995 , vol. 36, # 19 p. 3315 - 3316
反应条件
1: NaH / tetrahydrofuran; diethyl ether / 1.) 1 h, 2.) -5 to 5 deg C, 1 h
2: toluene / 1 h / Heating
View Scheme
参考文献
Jordis, Ulrich; Grohmann, Franz; Kueenburg, Bernhard
Organic Preparations and Procedures International, 1997 , vol. 29, # 5 p. 549 - 560
反应条件
sodium hydride
2) 140 deg C; Yield given. Multistep reaction;
参考文献
Nagashima, Hideo; Wakamatsu, Hidetoshi; Ozaki, Nobuyasu; Ishii, Tsutomu; Watanabe, Masakazu; et al.
Journal of Organic Chemistry, 1992 , vol. 57, # 6 p. 1682 - 1689
