2-甲基-3-丁炔-2-醇合成路线 （共 621 条）
反应条件
2: 22 percent / K2CO3, KI / ethanol / 14 h / Heating 3: 98 percent / H2 / Pd/carbon / methanol / 2 h / 2068.6 Torr View Scheme
参考文献
Synthetic Communications, , vol. 14, # 8 p. 737 - 742
反应条件
diisopropylammonium bromide; [(t-Bu)3PH]BF4; copper(l) iodide; Na2[PdCl4] in various solvent(s) T=80°C; Sonogashira coupling; 20 h;
参考文献
Koellhofer, Axel; Plenio, Herbert
Advanced Synthesis and Catalysis, 2005 , vol. 347, # 9 p. 1295 - 1300
反应条件
bis-triphenylphosphine-palladium(II) chloride; triethylamine; copper(l) chloride T=80°C;
参考文献
Watanabe, Jun-Ichi; Yokoyama, Harumi; Okada, Shuji; Takaragi, Shigeru; Matsuda, Hiro; Nakanishi, Hachiro
Molecular Crystals and Liquid Crystals, 2009 , vol. 505, # 1 p. 441 - 447
参考文献
Barnes et al.
Journal of Pharmacy and Pharmacology, 1958 , vol. 10, p. 315,317
反应条件
quinoline; diethyl ether und Behandeln der Reaktionsloesung mit Ammoniak;
参考文献
Schering A.G.
Patent: US2816910 , 1953 ;
Full Text Show Details
Schering A.G.
Patent: DE1007764 , 1952 ;
反应条件
1.1: 55 percent / POCl3; Et3N / CHCl3 / 15 h / 10 - 20 °C 2.1: 72 percent / H2 / Pd/C / methanol / 16 h / 1551.44 Torr 3.1: LDA / tetrahydrofuran; heptane; ethylbenzene / 0.5 h / -78 °C 3.2: 70 percent / tetrahydrofuran; heptane; ethylbenzene / -78 °C 4.1: Et3N; MeSO2Cl / tetrahydrofuran / 20 °C View Scheme
参考文献
Saimoto, Hiroyuki; Hiyama, Tamejiro; Nozaki, Hitosi
Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 10 p. 3078 - 3087
参考文献
Francis,T.; Thorne,M.P.
Canadian Journal of Chemistry, 1976 , vol. 54, p. 24 - 30
反应条件
sodium hydroxide; 2,2'-azo-bisisobutyronitrile in dichloromethane T=0 - 20°C; 3 h; Product distribution; Further Variations:ReagentsSolventsTemperatures;
参考文献
Calleja-Rubio; Crette; Blancou
Synthesis, 2003 , # 3 p. 361 - 364
参考文献
Nepera Chem.Co.
Patent: US2657241 , 1952 ;
反应条件
(i) benzene, (ii) aq. HCl; Multistep reaction;
参考文献
Shikhiev,I.A. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1962 , vol. 32, # 11 p. 3630 - 3633,3561 - 3564
