2-甲基-3-丁炔-2-醇合成路线 （共 621 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride; triethylamine
参考文献
Havens, Stephen J.; Hergenrother, Paul M.
Journal of Organic Chemistry, 1985 , vol. 50, # 10 p. 1763 - 1765
反应条件
1: 93 percent / Et3N; PPh3; CuI / Pd(OAc)2 / benzene / 0.67 h / 75 - 80 °C 2: 92 percent / NaBH4 / methanol / -20 °C View Scheme
参考文献
Klyatskaya, S. V.; Tretyakov, E. V.; Vasilevsky, S. F.
Russian Chemical Bulletin, 2002 , vol. 51, # 1 p. 128 - 134
Izvestiya Akademi Nauk, Seriya Khimicheskaya, 2002 , # 1 p. 122 - 127
反应条件
1: 3-methyliodobenzene; 2-methyl-but-3-yn-2-ol With copper(l) iodide; diisopropylamine; bis-triphenylphosphine-palladium(II) chloride in toluene T=80°C; Sonogashira coupling; 1 h; 2: iodobenzene With sodium hydride T=110°C; Sonogashira coupling;
参考文献
Novak, Zoltan; Nemes, Peter; Kotschy, Andras
Organic Letters, 2004 , vol. 6, # 26 p. 4917 - 4920
反应条件
phosphorus trichoride in dichloromethane
参考文献
Enchev
Phosphorus, Sulfur and Silicon and the Related Elements, 2008 , vol. 183, # 11 p. 2649 - 2654
反应条件
N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate; Copper(I)chloride in acetonitrile
参考文献
Loyola University of Chicago
Patent: US5231232 A1, 1993 ;
反应条件
copper(l) iodide; potassium carbonate; sodium sulfite; 1,8-diazabicyclo[5.4.0]undec-7-ene in dimethyl sulfoxide T=30°C; 4 h;
参考文献
Bieber, Lothar W.; da Silva, Margarete F.
Tetrahedron Letters, 2007 , vol. 48, # 40 p. 7088 - 7090
反应条件
1: 2-methyl-but-3-yn-2-ol With copper(l) iodide; potassium carbonate; triethylamine in N,N-dimethyl-formamide 2 h; 2: 3-chloroprop-1-ene in N,N-dimethyl-formamide T=50 - 55°C; 8 h; Further stages.;
参考文献
Veliev; Agaev; Shatirova; Chalabieva; Geidarova; Alieva
Russian Journal of Applied Chemistry, 2006 , vol. 79, # 11 p. 1829 - 1834
参考文献
Catellani,M. et al.
Journal of Organometallic Chemistry, 1978 , vol. 146, p. C19 - C22
反应条件
(i) , (ii) (pyrolysis); Multistep reaction;
参考文献
Surmatis,J.D.; Ofner,A.
Journal of Organic Chemistry, 1963 , vol. 28, p. 2735 - 2739
反应条件
polyvanadioorganosiloxane (3.1percent V) in xylene T=150 - 160°C; 6 h; MechanismRate constantProduct distribution;
参考文献
Journal of Organic Chemistry USSR (English Translation), , p. 21 - 28
Zhurnal Organicheskoi Khimii, , vol. 16, # 1 p. 23 - 31
