2-甲基-3-丁炔-2-醇合成路线 （共 621 条）
反应条件
1: p-iodo-[(tetrahydro-2H-pyran-2-yl)oxy]benzene With copper(l) iodide; triphenylphosphine; palladium dichloride; triethylamine T=50°C; 0.5 h; 2: 2-methyl-but-3-yn-2-ol T=85°C; 5 h;
参考文献
Lai, Guo-Qiao; Liu, Shi-Ling; Xu, Jin-Feng; Shen, Yong-Jia
Journal of Chemical Research, 2006 , # 3 p. 203 - 204
反应条件
potassium acetate; silver(l) oxide in dichloromethane T=20°C; 24 h;
参考文献
European Journal of Organic Chemistry, , # 21 p. 3476 - 3479
反应条件
in dichloromethane at -50°C, warming to room temp. and stirring for 45 min; tlc (silica gel, acetone-hexane 1:4), recrystn. from CH2Cl2-MeOH; elem.anal.;
参考文献
Journal of the Chemical Society, Dalton Transactions, , # 6 p. 881 - 890
反应条件
1: 2-methyl-but-3-yn-2-ol With copper(l) iodide; P-olefin; triethylamine; bis(dibenzylideneacetone)-palladium(0) in N,N-dimethyl-formamide 0.0833333 h; Inert atmosphere; 2: 1-bromo-2-phenylacetylene in N,N-dimethyl-formamide T=20 - 25°C; 9 h; Inert atmosphere;
参考文献
Shi, Wei; Luo, Yingdong; Luo, Xiancai; Chao, Lei; Zhang, Heng; Wang, Jian; Lei, Aiwen
Journal of the American Chemical Society, 2008 , vol. 130, # 44 p. 14713 - 14720
反应条件
copper acetylacetonate; iron (III) acetylacetonate; potassium carbonate in N,N-dimethyl-formamide T=50°C; 12 h;
参考文献
Tetrahedron, , vol. 66, # 23 p. 4029 - 4031
反应条件
copper(l) iodide; triethylamine in N,N-dimethyl-formamide T=20°C; 16 h; Inert atmosphere;
参考文献
Li, Hongling; Wang, Lailai; Yang, Min; Qi, Yanxing
Catalysis Communications, 2012 , vol. 17, p. 179 - 183
反应条件
copper(l) iodide; N,N,N',N,-tetramethylethylenediamine; triethylamine in acetone T=20°C; 20 h;
参考文献
Zhang, Songlin; Liu, Xiaoyan; Wang, Tongqiang
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 9 p. 1463 - 1466
反应条件
sulfuric acid; water; dihydrogen peroxide
参考文献
Milas; Mageli
Journal of the American Chemical Society, 1952 , vol. 74, p. 1471
Full Text View citing articles Show Details
Balandin et al.
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1959 , p. 1177,1183, 1184; engl. Ausg. S. 1138, 1143, 1144
参考文献
Milas; Mageli
Journal of the American Chemical Society, 1952 , vol. 74, p. 1471
反应条件
1: iodobenzene; 2-methyl-but-3-yn-2-ol With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine
T=50°C; 1 h; Inert atmosphere;
2: para-nitro iodo-benzene With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; potassium hydroxide
T=110°C; 5 h; Inert atmosphere;
参考文献
Zhao, Yankai; Liu, Qiang; Li, Jing; Liu, Zhongquan; Zhou, Bo
Synlett, 2010 , # 12 p. 1870 - 1872
