2-甲基-3-丁炔-2-醇合成路线 （共 621 条）
反应条件
hypophosphorous ether in benzene
Heating;
参考文献
Belakhov, V. V.; Yudelevich, V. I.; Komarov, E. V.; Ionin, B. I.; Komarov, V. Ya.; et al.
J. Gen. Chem. USSR (Engl. Transl.), 1983 , vol. 53, # 7 p. 1493 - 1503,1345 - 1353
反应条件
1.1: copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); potassium hydroxide / diethylamine; tetrahydrofuran / 12 h / 0 - 20 °C
2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.25 h / 0 °C
2.2: 0 - 20 °C
View Scheme
参考文献
Geary, Laina M.; Leung, Joyce C.; Krische, Michael J.
Chemistry - A European Journal, 2012 , vol. 18, # 52 p. 16823 - 16827
反应条件
hydrogenchloride; triethylamine; tetrakis (triphenylphosphine) palladium (0) in water; ethyl acetate; N,N-dimethyl-formamide
参考文献
Dainippon Ink and Chemicals, Incorporated
Patent: EP1640433 A1, 2006 ;
反应条件
1: propionic acid / 140 - 150 °C
2: LiAlH4 / tetrahydrofuran / 0 - 25 °C
3: Dess-Martin periodinane / CH2Cl2 / 20 °C
4: diethyl ether; tetrahydrofuran / -78 °C
View Scheme
参考文献
Xu, Daiwang; Lu, Zhan; Li, Zuyi; Ma, Shengming
Tetrahedron, 2004 , vol. 60, # 51 p. 11879 - 11887
反应条件
boron trifluoride diethyl etherate in dichloromethane
T=20°C; 6.5 h;
参考文献
Madabhushi, Sridhar; Jillella, Raveendra; Godala, Kondal Reddy; Mallu, Kishore Kumar Reddy; Beeram, China Ramanaiah; Chinthala, Narsaiah
Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5275 - 5279
反应条件
1: 90 percent / Zn / CH2Cl2 / 2 h / 45 °C
2: 91 percent / KOH / H2O; ethanol / 1.5 h
View Scheme
参考文献
Calas, Patrick; Moreau, Patrice; Commeyras, Auguste
Journal of the Chemical Society, Chemical Communications, 1982 , # 8 p. 433 - 434
反应条件
sodium hydroxide; 2,2'-azo-bisisobutyronitrile in dichloromethane
T=0 - 20°C; 3 h; Product distribution; Further Variations:SolventsTemperaturesreaction time;
参考文献
Calleja-Rubio; Crette; Blancou
Synthesis, 2003 , # 3 p. 361 - 364
反应条件
in N,N-dimethyl-formamide
9 h; electrolysis; Rate constantMechanism;
参考文献
Calas, P.; Amatoire, C.
Journal of Fluorine Chemistry, 1990 , vol. 49, # 2 p. 247 - 261
反应条件
1: 90 percent / Zn / CH2Cl2 / 2 h / 45 °C
2: 93 percent / KOH / H2O; ethanol / 1.5 h
View Scheme
参考文献
Calas, Patrick; Moreau, Patrice; Commeyras, Auguste
Journal of the Chemical Society, Chemical Communications, 1982 , # 8 p. 433 - 434
反应条件
potassium hydroxide; sodium carbonate; e- (carbon)
1.) electro catalyst, r.t., 2.) methanol, r.t.; Yield given;
参考文献
Moreau, Patrice; Naji, Naima; Commeyras, Auguste
Journal of Fluorine Chemistry, 1985 , vol. 30, p. 315 - 328
