2-甲基-3-丁炔-2-醇合成路线 （共 621 条）
反应条件
tetrabutyl ammonium fluoride; copper diacetate in 1,4-dioxane
T=30°C;
参考文献
Arsenyan, Pavel; Petrenko, Alla; Paegle, Edgars; Belyakov, Sergey
Mendeleev Communications, 2011 , vol. 21, # 6 p. 326 - 328
反应条件
copper (I) iodide; diethylamine; bis-triphenylphosphine-palladium(II) chloride
T=40°C; Sonogashira reaction; 1 h;
参考文献
Rodriguez, J. Gonzalo; De Los Rios, Cristobal; Lafuente, Antonio
Tetrahedron, 2005 , vol. 61, # 38 p. 9042 - 9051
反应条件
water; potassium hydroxide in dimethyl sulfoxide
T=20 - 80°C; 1 h; stereoselective reaction;
参考文献
Schmidt, Elena Yu.; Bidusenko, Ivan A.; Zorina, Nadezhda V.; Ushakov, Igor A.; Mikhaleva, Al'Bina I.; Klyba, Ludmila V.; Trofimov, Boris A.
Mendeleev Communications, 2012 , vol. 22, # 3 p. 132 - 133
反应条件
potassium hydroxide; diethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide
2.) MeOH, reflux; Multistep reaction;
参考文献
Novak, Igor; Ng, Siu Choon; Fang, Jiye; Mok, Chup Yew; Huang, Hsing Hua
Journal of Physical Chemistry, 1994 , vol. 98, # 3 p. 748 - 751
反应条件
copper(l) iodide; diethylamine; triphenylphosphine; palladium diacetate
48 h; Heating;
参考文献
Li, Yuanzhen; Zou, Haixia; Gong, Jianxian; Xiang, Jing; Luo, Tuoping; Quan, Junmin; Wang, Guoxin; Yang, Zhen
Organic Letters, 2007 , vol. 9, # 20 p. 4057 - 4060
反应条件
copper(l) iodide; tetra-(n-butyl)ammonium iodide; diethylamine; bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide
T=70°C; 2.5 h;
参考文献
Mori, Hajime; Matsuo, Takafumi; Yoshioka, Yasunori; Katsumura, Shigeo
Journal of Organic Chemistry, 2006 , vol. 71, # 24 p. 9004 - 9012
反应条件
potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide
T=100°C; 6 h;
参考文献
Oi, Shuichi; Orihara, Hideki; Kawai, Hiroshi; Inoue, Yoshio
Heterocycles, 2005 , vol. 66, # 1 p. 621 - 625
反应条件
potassium acetate; silver(l) oxide in dichloromethane
T=20°C; 24 h;
参考文献
Yang, Fan; Wu, Yangjie
European Journal of Organic Chemistry, 2007 , # 21 p. 3476 - 3479
反应条件
1: 90.5 percent / chlorine; NaOH / H2O; benzene / 1 h / 20 °C
2: magnesium / methoxybenzene; tetrahydrofuran / 4 h / 40 - 45 °C
View Scheme
参考文献
Shchelkunov; Sivolobova; Mataeva; Minbaev; Muldakhmetov
Russian Journal of Organic Chemistry, 2001 , vol. 37, # 1 p. 5 - 8
反应条件
[rhenium(I)pentacarbonyl(chloride)] in hexane
T=60°C; 24 h;
参考文献
Zeng, Hanxiang; Ju, Jia; Hua, Ruimao
Tetrahedron Letters, 2011 , vol. 52, # 30 p. 3926 - 3928
