2-甲基-3-丁炔-2-醇合成路线 （共 621 条）
反应条件
tris(triphenylphosphine)platinum (0)
参考文献
Singer,H.; Wilkinson,G.
Journal of the Chemical Society [Section] A: Inorganic, Physical, Theoretical, 1968 , p. 849 - 853
反应条件
potassium hydroxide in ethanol
参考文献
Glazunova,E.M. et al.
Zhurnal Organicheskoi Khimii, 1976 , vol. 12, p. 516 - 521,508 - 512
反应条件
sodium methylate; copper in ethanol
T=25°C; 11 h; Schlenk techniqueInert atmosphereSealed tube; regioselective reaction;
参考文献
Zhao, Jie; Niu, Zhiqiang; Fu, Hua; Li, Yadong
Chemical Communications, 2014 , vol. 50, # 16 p. 2058 - 2060
反应条件
ammonia; lithium; iron nitrate (III) in diethyl ether
T=-40°C; 1 h;
参考文献
Mayr, Herbert; Halberstadt-Kausch, Inge K.
Chemische Berichte, 1982 , vol. 115, # 11 p. 3479 - 3515
反应条件
carbon dioxide; sodium acetate; copper dichloride in methanol
T=40°C; P=105008 Torr; 4 h;
参考文献
Jiang, Huan-Feng; Tang, Jin-Yu; Wang, A.-Zhong; Deng, Guo-Hua; Yang, Shao-Rong
Synthesis, 2006 , # 7 p. 1155 - 1161
反应条件
copper acetylacetonate; iron (III) acetylacetonate; potassium carbonate in N,N-dimethyl-formamide
T=50°C; 12 h;
参考文献
Meng, Xu; Li, Chuanbin; Han, Baochun; Wang, Tiansheng; Chen, Baohua
Tetrahedron, 2010 , vol. 66, # 23 p. 4029 - 4031
反应条件
copper(l) iodide; ethyl α,α-dibromoacetoacetate; triethylamine in dichloromethane
T=20°C; 23 h; Overall yield = 99 percent;
参考文献
Fan, Xiaohui; Li, Na; Shen, Tong; Cui, Xiao-Meng; Lv, Hao; Zhu, Hong-Bo; Guan, Yong-Hong
Tetrahedron, 2014 , vol. 70, # 2 p. 256 - 261
反应条件
copper acetylacetonate; iron (III) acetylacetonate; potassium carbonate in N,N-dimethyl-formamide
T=50°C; 24 h;
参考文献
Meng, Xu; Li, Chuanbin; Han, Baochun; Wang, Tiansheng; Chen, Baohua
Tetrahedron, 2010 , vol. 66, # 23 p. 4029 - 4031
反应条件
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-ethyl-N,N-diisopropylamine; triphenylphosphine in toluene
T=85°C; Sonogashira cross-coupling; Inert atmosphere;
参考文献
Kane, Christopher M.; Meyers, Tiffany B.; Yu, Xin; Gerken, Michael; Etzkorn, Markus
European Journal of Organic Chemistry, 2011 , # 16 p. 2969 - 2980
反应条件
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-ethyl-N,N-diisopropylamine in toluene
T=85°C; Sonogashira cross-coupling; Inert atmosphere;
参考文献
Kane, Christopher M.; Meyers, Tiffany B.; Yu, Xin; Gerken, Michael; Etzkorn, Markus
European Journal of Organic Chemistry, 2011 , # 16 p. 2969 - 2980
