2-甲基-3-丁炔-2-醇合成路线 （共 621 条）
反应条件
diisopropylamine; triphenylphosphine; ferrocenyl-based palladium(II) in N,N-dimethyl-formamide
T=100°C; Sonogashira coupling;
参考文献
Nagy, Tibor Zs.; Csampai, Antal; Kotschy, Andras
Tetrahedron, 2005 , vol. 61, # 41 p. 9767 - 9774
反应条件
1: 90.5 percent / chlorine; NaOH / H2O; benzene / 1 h / 20 °C
2: 63.2 percent / magnesium / methoxybenzene; tetrahydrofuran / 4 h / 40 - 45 °C
View Scheme
参考文献
Shchelkunov; Sivolobova; Mataeva; Minbaev; Muldakhmetov
Russian Journal of Organic Chemistry, 2001 , vol. 37, # 1 p. 5 - 8
反应条件
3,4-dihydroxy-1-tert-butylbenzene; ammonium chloride; copper(l) chloride; phosphorus trichoride
参考文献
Bergmann; Herrman
Journal of the American Chemical Society, 1951 , vol. 73, p. 4013
反应条件
1: NH4Cl; CuCl; HCl
2: CuCl; NH4Cl
3: CaCO3; water
View Scheme
参考文献
Faworski; Faworskaja
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1935 , vol. 200, p. 839
反应条件
2,2'-dihydroxy-1,1'-biphenyl; α-cyclohexylcyclohexanemethanamine; indium tribromide in dichloromethane
T=40°C; 24 h; Product distribution; Further Variations:Reagentstime, concentration of reagent;
参考文献
Harada, Shinji; Takita, Ryo; Ohshima, Takashi; Matsunaga, Shigeki; Shibasaki, Masakatsu
Chemical Communications, 2007 , # 9 p. 948 - 950
反应条件
diethyl ether
anschliessend Behandeln mit Benzaldehyd;
参考文献
Salkind; Iwanow
Zhurnal Obshchei Khimii, 1941 , vol. 11, p. 803,810, 815
Chem.Abstr., 1942 , p. 3790
反应条件
methanol; mercury(II) oxide; trichloroacetic acid
Reagens 4: Borfluorid-Aether-Addukt;
参考文献
Hennion; Murray
Journal of the American Chemical Society, 1942 , vol. 64, p. 1220
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Nasarow
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1940 , p. 219
Chem.Abstr., 1942 , p. 746
反应条件
1: 90 percent / PPh3, CuI / PdCl2 / triethylamine; dimethylformamide / 0.8 h / 85 °C
2: 91 percent / K2CO3 / ethanol / 1.5 h / Heating
View Scheme
参考文献
Sogawa, Akihiro; Tsukayama, Masao; Nozaki, Hiroshi; Nakayama, Mitsuru
Heterocycles, 1996 , vol. 43, # 1 p. 101 - 111
反应条件
trans-{bis(tricyclohexylphosphine)Pd(II)(H)(H2O)}BF4; toluene-4-sulfonic acid; 1,4-di(diphenylphosphino)-butane in tetrahydrofuran
T=100°C; P=15200 Torr; 48 h;
参考文献
Huh, Keun-Tae; Orita, Akihiro; Alper, Howard
Journal of Organic Chemistry, 1993 , vol. 58, # 25 p. 6956 - 6957
反应条件
ethylamine; copper(l) chloride
参考文献
Chodkiewicz
Annales de Chimie (Cachan, France), 1957 , vol. <13> 2, p. 819,861, 862
