2-甲基-3-丁炔-2-醇合成路线 （共 621 条）
反应条件
copper(l) iodide; diethylamine; triphenylphosphine; palladium diacetate 36 h; Heating;
参考文献
Zou, Haixia; Zhou, Liyan; Li, Yuanzhen; Cui, Yi; Zhong, Hanbing; Pan, Zhengying; Yang, Zhen; Quan, Junmin
Journal of Medicinal Chemistry, 2010 , vol. 53, # 3 p. 994 - 1003
反应条件
copper(l) iodide; triethylamine; triphenylphosphine T=90°C; Sonogashira coupling; 3 h; Inert atmosphere;
参考文献
Lin, Bo-Nan; Huang, Shao-Hsien; Wu, Wei-Yi; Mou, Chung-Yuan; Tsai, Fu-Yu
Molecules, 2010 , vol. 15, # 12 p. 9157 - 9173
反应条件
copper(l) iodide; N-ethyl-N,N-diisopropylamine; tetrakis(triphenylphosphine) palladium(0) in water T=70°C; Sonogashira reaction; 0.5 h;
参考文献
Bhattacharya, Santanu; Sengupta, Saumitra
Tetrahedron Letters, 2004 , vol. 45, # 47 p. 8733 - 8736
反应条件
silver(l) oxide; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=60°C; 6 h;
参考文献
Ahmed, Mohamed S. Mohamed; Sekiguchi, Akitoshi; Shimada, Tomohiro; Kawashima, Jun; Mori, Atsunori
Bulletin of the Chemical Society of Japan, 2005 , vol. 78, # 2 p. 327 - 330
反应条件
copper(l) iodide; sodium hydrogencarbonate in ethylene glycol dimethyl ether; water T=20°C; 0.5 h;
参考文献
Kang, Suk-Ku; Yoon, Seok-Keun; Kim, Young-Mook
Organic Letters, 2001 , vol. 3, # 17 p. 2697 - 2699
反应条件
potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=100°C; 6 h;
参考文献
Heterocycles, , vol. 66, # 1 p. 621 - 625
反应条件
triethylamine; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=100°C; Sonogashira reaction; 6 h;
参考文献
Heterocycles, , vol. 66, # 1 p. 621 - 625
反应条件
potassium carbonate in water copper-free Sonogashira coupling; 12 h; Reflux;
参考文献
Khalafi-Nezhad, Ali; Panahi, Farhad
Green Chemistry, 2011 , vol. 13, # 9 p. 2408 - 2415
反应条件
ethylmagnesium bromide in diethyl ether
参考文献
Shchelkunov; Sivolobova; Mataeva; Minbaev; Muldakhmetov
Russian Journal of Organic Chemistry, 2001 , vol. 37, # 1 p. 5 - 8
反应条件
1: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide in diethylamine T=20°C; 15 h; 2: With sodium hydroxide in toluene 1 h; Heating;
参考文献
Lottermoser, Ursula; Rademacher, Paul; Mazik, Monika; Kowski, Klaus
European Journal of Organic Chemistry, 2005 , # 3 p. 522 - 531
