2-甲基-3-丁炔-2-醇合成路线 （共 621 条）
参考文献
Dzhemilev, U. M.; Selimov, F. A.; Rutman, O. G.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1988 , vol. 37, # 11 p. 2343 - 2346
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1988 , # 11 p. 2600 - 2604
反应条件
potassium hydroxide; diethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide 2.) MeOH, reflux; Multistep reaction;
参考文献
Novak, Igor; Ng, Siu Choon; Fang, Jiye; Mok, Chup Yew; Huang, Hsing Hua
Journal of Physical Chemistry, 1994 , vol. 98, # 3 p. 748 - 751
反应条件
piperidine; caesium carbonate; [(P{(C6H11)3})2Pd(Cl)2] in dimethyl sulfoxide T=120°C; Sonogashira coupling; 12 h;
参考文献
Yi, Chenyi; Hua, Ruimao; Zeng, Hanxiang; Huang, Qiufeng
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 10 p. 1738 - 1742
反应条件
tert.-butylhydroperoxide; potassium iodide in methanol; water T=20°C; 6 h;
参考文献
Rajender Reddy; Venkateshwar; Uma Maheswari; Santhosh Kumar
Tetrahedron Letters, 2010 , vol. 51, # 16 p. 2170 - 2173
反应条件
1: mercury sulfate; diluted sulfuric acid 2: aqueous-alcoholic NaOH-solution View Scheme
参考文献
Scheibler; Fischer
Chemische Berichte, 1922 , vol. 55, p. 2918
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine in tetrahydrofuran 20 h; Ambient temperature;
参考文献
Maya, Eva M.; Haisch, Peter; Vazquez, Purificacion; Torres, Tomas
Tetrahedron, 1998 , vol. 54, # 17 p. 4397 - 4404
反应条件
1: |Schlenk technique; |Inert atmosphere 2: C16H20N2O3 / neat (no solvent) / 24 h / 60 °C / 15001.5 Torr / |Autoclave; |Schlenk technique; |Inert atmosphere View Scheme
参考文献
Wang, Yan-Bo; Sun, Dong-Sheng; Zhou, Hui; Zhang, Wen-Zhen; Lu, Xiao-Bing
Green Chemistry, 2014 , vol. 16, # 4 p. 2266 - 2272
反应条件
sodium hydride in tetrahydrofuran; mineral oil T=20°C;
参考文献
Schimler, Sydonie D.; Hall, David J.; Debbert, Stefan L.
Journal of Inorganic Biochemistry, 2013 , vol. 119, p. 28 - 37
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran; dichloromethane 65 h;
参考文献
Subramanian, R. Sankara; Balasubramanian, K. K.
Synthetic Communications, 1989 , vol. 19, # 7,8 p. 1255 - 1260
反应条件
1: n-butyl lithium 2: 78 percent / 0.3 mole percent CuCl2 * 2 H2O, 1,8-diazabicyclo<5.4.0>undec-7-ene / acetonitrile / 24 h / 0 °C View Scheme
参考文献
Godfrey, Jollie D.; Mueller, Richard H.; Sedergran, Thomas C.; Soundarajan, Nachimuthu; Colandrea, Vincent J.
Tetrahedron Letters, 1994 , vol. 35, # 35 p. 6405 - 6408
