3-羟基-3-甲基-2-丁酮合成路线 （共 82 条）
反应条件
1.1: nBuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C
1.2: 70 percent / tetrahydrofuran; hexane / 3 h / -78 °C
2.1: cerium(III) chloride heptahydrate; sodium iodide / acetonitrile / 3 h / Heating
2.2: 80 percent / HCl / acetonitrile; H2O; diethyl ether
View Scheme
参考文献
Palomo, Claudio; Oiarbide, Mikel; Arceo, Elena; Garcia, Jesus M.; Lopez, Rosa; Gonzalez, Alberto; Linden, Anthony
Angewandte Chemie - International Edition, 2005 , vol. 44, # 38 p. 6187 - 6190
反应条件
lithium hydroxide; water in tetrahydrofuran; water
T=20°C;
参考文献
Chiang, Pei-Chen; Kim, Yoonjoo; Bode, Jeffrey W.
Chemical Communications, 2009 , # 30 p. 4566 - 4568
