5-(乙氧基羰基)噻吩-2-硼酸频那醇酯合成路线 (共 2 条)
反应条件
bis(η4-1,5-cyclooctadiene)-di-μ-methoxy-diiridium(I); 4,4'-di-tert-butyl-2,2'-dipyridyl in hexane T=20°C; 12 h; Inert atmosphere;
参考文献
AMGEN INC.; ASHTON, Kate; BARTBERGER, Michael D.; BOURBEAU, Matthew Paul; CROGHAN, Michael D.; FOTSCH, Christopher H.; HUNGATE, Randall W.; KONG, Ke; NISHIMURA, Nobuko; NORMAN, Mark H.; PENNINGTON, Lewis D.; REICHELT, Andreas; SIEGMUND, Aaron C.; TADESSE, Seifu; ST. JEAN, David Jr; YANG, Kevin C.; YAO, Guomin
Patent: WO2013/173382 A1, 2013 ;
Location in patent: Page/Page column 197 ;
反应条件
1: CsF-Diatomaceous earth / acetonitrile / 12 h / 80 °C 2: bis(η4-1,5-cyclooctadiene)-di-μ-methoxy-diiridium(I); 4,4'-di-tert-butyl-2,2'-dipyridyl / hexane / 12 h / 20 °C / |Inert atmosphere View Scheme