1: 41 percent / 80percent AcOH / 40 h / 45 °C 2: 0.1N NaOH / CH2Cl2; methanol / 0.33 h / 0 °C 3: 0.1N NaOH / CH2Cl2; methanol / 0.33 h / Ambient temperature View Scheme

With  acetic acid T=45°C; 40 h;