6-氯咪唑并[1,2-B]吡嗪-3-羧酸乙酯合成路线 （共 3 条）
反应条件
N-ethyl-N,N-diisopropylamine in acetonitrile T=20°C; 4 h;
参考文献
CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO)
Patent: WO2009/60197 A1, 2009 ;
Location in patent: Page/Page column 59 ;
WO 2009/060197 A1
反应条件
in ethanol 10 h; Reflux;
参考文献
SIRTRIS PHARMACEUTICALS, INC.; CASAUBON, Rebecca, L.; NARAYAN, Radha; OALMANN, Christopher; VU, Chi, B.
Patent: WO2013/59587 A1, 2013 ;
Location in patent: Page/Page column 75 ;
反应条件
1: acetonitrile / 3 h / 85 °C 2: N-ethyl-N,N-diisopropylamine / acetonitrile / 3 h / 20 °C View Scheme
参考文献
IRM LLC
Patent: US2012/65184 A1, 2012 ;
US 20120065184 A1
