5-溴-4-甲基-1H-吡咯并[2,3-b]吡啶合成路线 （共 3 条）
反应条件
potassium tert-butylate in 1-methyl-pyrrolidin-2-one T=80°C;
参考文献
US2011/82138 A1, ;
Page/Page column 32 ;
US 20110082138 A1
反应条件
1.1: trifluoroacetic acid; N-iodo-succinimide / acetic acid / 2.5 h / 20 °C 1.2: Cooling 2.1: triethylamine; copper(l) iodide / bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 20 °C / Inert atmosphere 3.1: potassium tert-butylate / 1-methyl-pyrrolidin-2-one / 80 °C View Scheme
参考文献
US2011/82138 A1, ;
US 20110082138 A1
反应条件
1: triethylamine; copper(l) iodide / bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 20 °C / Inert atmosphere 2: potassium tert-butylate / 1-methyl-pyrrolidin-2-one / 80 °C View Scheme
参考文献
US2011/82138 A1, ;
US 20110082138 A1
