1: in ethyl acetate T=20°C; 2 h; 2: With sodium hydroxide in water; ethyl acetate pH=12; Cooling with ice;

1.1: hydrogen / palladium 10 on activated carbon / tetrahydrofuran / 25 °C / Autoclave; Inert atmosphere 2.1: hydrogenchloride; sodium nitrite / water / 0 - 5 °C 2.2: 1.5 h / 10 - 50 °C 2.3: pH 8 3.1: ethyl acetate / 2 h / 20 °C 3.2: pH 12 / Cooling with ice View Scheme

1.1: hydrogenchloride; sodium nitrite / water / 0 - 5 °C 1.2: 1.5 h / 10 - 50 °C 1.3: pH 8 2.1: ethyl acetate / 2 h / 20 °C 2.2: pH 12 / Cooling with ice View Scheme