3-溴-4-甲基-5-硝基-2-吡啶羧酸甲酯合成路线 （共 4 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride; triethylamine in acetonitrile T=70°C; 16 h;
参考文献
MedChemComm, , vol. 4, # 4 p. 709 - 719
反应条件
1: sodium iodide; chloro-trimethyl-silane; anhydrous propionitrile / 16 h / 20 °C 2: triethylamine; bis-triphenylphosphine-palladium(II) chloride / acetonitrile / 16 h / 70 °C View Scheme
参考文献
MedChemComm, , vol. 4, # 4 p. 709 - 719
反应条件
1: bromine; acetic acid / 3 h / 20 °C 2: trichlorophosphate / acetonitrile / 6 h / 20 °C 3: sodium iodide; chloro-trimethyl-silane; anhydrous propionitrile / 16 h / 20 °C 4: triethylamine; bis-triphenylphosphine-palladium(II) chloride / acetonitrile / 16 h / 70 °C View Scheme
参考文献
MedChemComm, , vol. 4, # 4 p. 709 - 719
反应条件
1: trichlorophosphate / acetonitrile / 6 h / 20 °C 2: sodium iodide; chloro-trimethyl-silane; anhydrous propionitrile / 16 h / 20 °C 3: triethylamine; bis-triphenylphosphine-palladium(II) chloride / acetonitrile / 16 h / 70 °C View Scheme
参考文献
MedChemComm, , vol. 4, # 4 p. 709 - 719
