3-叔丁氧羰基氨基-6-甲基哌啶合成路线 （共 3 条）
反应条件
hydrogen; acetic acid; platinum(IV) oxide in ethanol T=50°C; P=2844.39 Torr; 72 h;
参考文献
PFIZER INC.; NINKOVIC, Sacha; BRAGANZA, John Frederick; COLLINS, Michael Raymond; KATH, John Charles; LI, Hui; RICHTER, Daniel Tyler
Patent: WO2010/16005 A1, 2010 ;
Location in patent: Page/Page column 135-136 ;
WO 2010/016005 A1
反应条件
1.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.25 h / 20 °C 1.2: 17 h / 20 °C 2.1: hydrogen; acetic acid / 5 rhodium-on-charcoal; platinum(IV) oxide / 7 h / 70 °C / 10343.2 Torr View Scheme
参考文献
AMGEN INC.; D'AMICO, Derin C.; HERBERICH, Bradley J.; JACKSON, Claire L.M.; PETTUS, Liping H.; TASKER, Andrew; WANG, Hui-Ling; WU, Bin; WURZ, Ryan
Patent: WO2012/148775 A1, 2012 ;
WO 2012/148775 A1
反应条件
1.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.25 h / 20 °C 1.2: 17 h / 20 °C 2.1: hydrogen; acetic acid / 5 rhodium-on-charcoal; platinum(IV) oxide / 7 h / 70 °C / 10343.2 Torr View Scheme
参考文献
AMGEN INC.; D'AMICO, Derin C.; HERBERICH, Bradley J.; JACKSON, Claire L.M.; PETTUS, Liping H.; TASKER, Andrew; WANG, Hui-Ling; WU, Bin; WURZ, Ryan
Patent: WO2012/148775 A1, 2012 ;
WO 2012/148775 A1
