4-甲氧基-4-硝基二苯甲酮合成路线 （共 39 条）
反应条件
1: Heating 2: CrO3, AcOH View Scheme
参考文献
Journal of the Chemical Society, , p. 366 - 373
参考文献
Angewandte Chemie, , vol. 84, p. 294 - 295
参考文献
Chemische Berichte, , vol. 36, p. 3898
参考文献
Chemische Berichte, , vol. 36, p. 3898
反应条件
1: Methyltriphenylphosphonium bromide With potassium tert-butylate in tetrahydrofuran T=20°C; Wittig Olefination; 1 h; 2: 4-(4-methoxybenzoyl)-nitrobenzene in tetrahydrofuran T=20°C; Wittig Olefination;
参考文献
Stocker, Vivien; Ghinet, Alina; Leman, Marie; Rigo, Benoit; Millet, Regis; Farce, Amaury; Desravines, Deborah; Dubois, Joelle; Waterlot, Christophe; Gautret, Philippe
RSC Advances, 2013 , vol. 3, # 11 p. 3683 - 3696
反应条件
tetrabutyl ammonium fluoride in dimethyl sulfoxide T=20°C; 0.5 h;
参考文献
Shani; Gazit; Livshitz; Biran
Journal of Medicinal Chemistry, 1985 , vol. 28, # 10 p. 1504 - 1511
反应条件
1: HBr; AcOH / Heating
2: K2CO3 / dimethylformamide / 60 - 70 °C
View Scheme
参考文献
Clark, Robin D.; Jahangir, Alam; Severance, Daniel; Salazar, Rick; Chang, Thomas; Chang, David; Jett, Mary Frances; Smith, Steven; Bley, Keith
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 4 p. 1053 - 1056
反应条件
1: 62 percent / Na2S2O4*H2O / ethanol / Heating
2: 1.) conc. aq. HCl, NaNO2 / 1.) H2O, 20 min, 2.) H2O, RT, 0.5 h
3: 37 percent / 40percent aq. HF / benzene / 1.) RT, 0.5 h, 2.) 50 deg C, 10 min
4: 1.) Mg / 2.) ether, 2.) ether, reflux, 4 h
5: 85 percent / BBr3 / CH2Cl2 / 1 h / Ambient temperature
6: KOH / ethanol / 20 h / Heating
View Scheme
参考文献
Shani; Gazit; Livshitz; Biran
Journal of Medicinal Chemistry, 1985 , vol. 28, # 10 p. 1504 - 1511
反应条件
hydrogenchloride; tin
Diazotieren des entstandenen Amins und Verkochen der Diazoniumloesung;
参考文献
Labor. Fournier
Patent: FR2300552DE2605382 , 19761976 ;
Chem.Abstr., 1976 , vol. 85, # 192382
