potassium tert-butylate 1.) DMF, 25 deg C, 2.) 110 deg C, 5h; Yield given. Multistep reaction;

1: 4N aq. NaOH / methanol / 1 h / 25 °C 2: 95 percent / NH2OH, Na2CO3 / H2O / 2 h 3: 96 percent / H2 / 10percent Pd/C / aq. acetic acid / 2 h / 25 °C / 2280 Torr View Scheme

1: 1.) molecular sieves 3A, 2.) NaBH3CN / 1.) MeOH, reflux, 6 h, 2.) 2 h 2: 70 percent / ammonium formate, H2 / 10percent Pd/C / ethanol / 50 h / 25 °C 3: 1.) 2N aq. NaOH / 1.) dioxane, 25 deg C, 2 h, 2.) dioxane, 25 deg C, 2 h View Scheme

sodium hydroxide in methanol T=25°C; 1 h; Yield given;