2: 70 percent / tetrabutylammonium fluoride / tetrahydrofuran / 2 h / Ambient temperature 3: 97 percent / pyridinium chlorochromate, sodium acetate, Celite / CH2Cl2 / 1.5 h / Ambient temperature 4: 71 percent / tetrahydrofuran; diethyl ether / 1.8 h / -78 - 0 °C 5: 95 percent / sodium acetate, pyridinium chlorochromate / CH2Cl2 / 2 h / Ambient temperature 6: 1.) sodium hydride / 1.) THF, RT, 1 h 2.) RT, overnight 7: 80 percent / 80percent aq CH3COOH / Ambient temperature 8: 77 percent / 1N aq NaHCO3, 1N aq KOH / ethanol; tetrahydrofuran / 4.5 h / 0 °C View Scheme

Multi-step reaction with 2 steps 1: 90 percent / NaI / butan-2-one / 1.5 h / Heating2: 81 percent / hexamethylphosphoric acid triamide / 0.5 h / Ambient temperature