5-O-(二甲氧基三苯甲游基)-2-o-甲基-5-甲基尿苷合成路线 （共 7 条）
反应条件
pyridine T=20°C; 4 h;
参考文献
Grover, Rajesh K.; Pond, Stephanie J. K.; Cui, Qizhi; Subramaniam, Prem; Case, David A.; Millar, David P.; Wentworth Jr., Paul
Angewandte Chemie - International Edition, 2007 , vol. 46, # 16 p. 2839 - 2843
反应条件
1: N-bromosuccinimide; azoisobutyronitrile / benzene / 0.67 h / 80 °C 2: 61 percent / NaOMe / 2 h 3: 78 percent / Et3N*3HF; pyridine / tetrahydrofuran / 16 h / 20 °C 4: 78 percent / pyridine / 4 h / 20 °C View Scheme
参考文献
Grover, Rajesh K.; Pond, Stephanie J. K.; Cui, Qizhi; Subramaniam, Prem; Case, David A.; Millar, David P.; Wentworth Jr., Paul
Angewandte Chemie - International Edition, 2007 , vol. 46, # 16 p. 2839 - 2843
反应条件
1: 61 percent / NaOMe / 2 h 2: 78 percent / Et3N*3HF; pyridine / tetrahydrofuran / 16 h / 20 °C 3: 78 percent / pyridine / 4 h / 20 °C View Scheme
参考文献
Grover, Rajesh K.; Pond, Stephanie J. K.; Cui, Qizhi; Subramaniam, Prem; Case, David A.; Millar, David P.; Wentworth Jr., Paul
Angewandte Chemie - International Edition, 2007 , vol. 46, # 16 p. 2839 - 2843
反应条件
1: 99 percent / imidazole / dimethylformamide / 2 h / 50 °C 2: N-bromosuccinimide; azoisobutyronitrile / benzene / 0.67 h / 80 °C 3: 61 percent / NaOMe / 2 h 4: 78 percent / Et3N*3HF; pyridine / tetrahydrofuran / 16 h / 20 °C 5: 78 percent / pyridine / 4 h / 20 °C View Scheme
参考文献
Grover, Rajesh K.; Pond, Stephanie J. K.; Cui, Qizhi; Subramaniam, Prem; Case, David A.; Millar, David P.; Wentworth Jr., Paul
Angewandte Chemie - International Edition, 2007 , vol. 46, # 16 p. 2839 - 2843
反应条件
1: 78 percent / Et3N*3HF; pyridine / tetrahydrofuran / 16 h / 20 °C 2: 78 percent / pyridine / 4 h / 20 °C View Scheme
参考文献
Grover, Rajesh K.; Pond, Stephanie J. K.; Cui, Qizhi; Subramaniam, Prem; Case, David A.; Millar, David P.; Wentworth Jr., Paul
Angewandte Chemie - International Edition, 2007 , vol. 46, # 16 p. 2839 - 2843
反应条件
1: Br2 / CCl4 / Irradiation 2: 2.1 g / methanol / 0.5 h 3: pyridine / 1 h / Ambient temperature View Scheme
参考文献
Takeda; Ikeda; Mizuno; Ueda
Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 9 p. 3558 - 3567
反应条件
1: 2.1 g / methanol / 0.5 h 2: pyridine / 1 h / Ambient temperature View Scheme
参考文献
Takeda; Ikeda; Mizuno; Ueda
Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 9 p. 3558 - 3567
