N-CBZ-L-天冬氨酸合成路线 （共 76 条）
反应条件
pyridine in dichloromethane T=0°C; 24 h; Yields of byproduct given;
参考文献
Jouin, P.; Castro, B.; Zeggaf, C.; Pantaloni, A.; Senet, J.P; et al
Tetrahedron Letters, 1987 , vol. 28, # 15 p. 1665 - 1668
反应条件
pyridine in dichloromethane T=0°C; 24 h; Yield given. Title compound not separated from byproducts;
参考文献
Jouin, P.; Castro, B.; Zeggaf, C.; Pantaloni, A.; Senet, J.P; et al
Tetrahedron Letters, 1987 , vol. 28, # 15 p. 1665 - 1668
反应条件
1.1: acetic anhydride / 16 h 2.1: ethyl acetate / 5 h / 20 °C 2.3: pH 2 View Scheme
参考文献
Chandan, Nandkishkor; Moloney, Mark G.
Tetrahedron Letters, 2013 , vol. 54, # 15 p. 1987 - 1990
参考文献
Heinzel, Wolfgang; Kronbach, Thomas; Voelter, Wolfgang
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1982 , vol. 37, # 12 p. 1652 - 1658
反应条件
acetic anhydride T=20 - 45°C; 2.25 h; Product distribution; Further Variations:ReagentsSolventsTemperatures;
参考文献
Buron, Frederic; Deguest, Geoffrey; Bischoff, Laurent; Fruit, Corinne; Marsais, Francis
Tetrahedron Asymmetry, 2007 , vol. 18, # 13 p. 1625 - 1627
反应条件
triethylamine in dichloromethane T=0°C; 1 h; Yield given. Title compound not separated from byproducts;
参考文献
Jouin, P.; Castro, B.; Zeggaf, C.; Pantaloni, A.; Senet, J.P; et al
Tetrahedron Letters, 1987 , vol. 28, # 15 p. 1665 - 1668
反应条件
triethylamine in dichloromethane T=0°C; 1 h; Yields of byproduct given;
参考文献
Jouin, P.; Castro, B.; Zeggaf, C.; Pantaloni, A.; Senet, J.P; et al
Tetrahedron Letters, 1987 , vol. 28, # 15 p. 1665 - 1668
反应条件
4-(N,N-dimethlyamino)pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane T=0 - 20°C; 20 h; Title compound not separated from byproducts.;
参考文献
Burtin, Guillaume; Corringer, Pierre-Jean; Young, Douglas W.
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 20 p. 3451 - 3459
反应条件
Aliquatreg; 336; sodium hydrogencarbonate in dichloromethane
参考文献
Bocchi,V. et al.
Synthesis, 1979 , p. 957 - 961
反应条件
1: (2S)-2-[(Phenylmethoxy)carbonyl]aminosuccinic acid With acetic anhydride T=45°C; 2: methanol Heating; 3: N,N-dicyclohexylamine Further stages.;
参考文献
Manturewicz; Grzonka
Polish Journal of Chemistry, 2007 , vol. 81, # 12 p. 2121 - 2131
