N-CBZ-L-天冬氨酸合成路线 (共 76 条)
反应条件
water T=170°C; 0.05 h; Microwave irradiation;
参考文献
Thaqi, Ali; McCluskey, Adam; Scott, Janet L.
Tetrahedron Letters, 2008 , vol. 49, # 49 p. 6962 - 6964
反应条件
pyridine in dichloromethane T=0°C; 18 h; var.time, var. reag.:Et3N, or add of cat.: DMAP; Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 28, # 15 p. 1665 - 1668
反应条件
pyridine in dichloromethane T=0°C; 24 h; Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 28, # 15 p. 1665 - 1668
反应条件
pyridine in dichloromethane T=0°C; 24 h; Yield given. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 28, # 15 p. 1665 - 1668
反应条件
1: 89 percent / KHCO3 / dimethylformamide / 12 h / 22 °C 2: 91 percent / aq. LiOH / tetrahydrofuran / 2 h / 0 °C View Scheme
参考文献
Tetrahedron, , vol. 53, # 48 p. 16575 - 16596
反应条件
1: 95 percent / Ac2O / 0.02 h / microwave irradiation 2: 80 percent / NaBH4 / tetrahydrofuran / 16 h / 20 °C View Scheme
参考文献
Luppi, Gianluigi; Tomasini, Claudia
Synlett, 2003 , # 6 p. 797 - 800
反应条件
in N-methyl-acetamide; water
参考文献
Toyo Soda Manufacturing Co. Ltd.; (Zaidanhojin) Sagami Chemical Research Center
Patent: US4165311 A1, 1979 ;
反应条件
sodium hydroxide; 15-crown-5 in N,N-dimethyl-formamide T=40°C; 2 h;
参考文献
Mazurov, A. A.; Antonenko, S. V.; Andronati, S. A.
Chemistry of Natural Compounds, 1986 , vol. 22, # 2 p. 208 - 210
Khimiya Prirodnykh Soedinenii, 1986 , vol. 22, # 2 p. 224 - 225
反应条件
toluene-4-sulfonic acid
参考文献
Davey; Laird; Morley
Journal of the Chemical Society. Perkin transactions 1, 1966 , vol. 5, p. 555 - 566
参考文献
Berger; Katchalski
Journal of the American Chemical Society, 1951 , vol. 73, p. 4084,4087