4,5-二甲基-1H-咪唑-2-甲醇合成路线 （共 3 条）
反应条件
sodium tetrahydroborate in methanol
参考文献
Skorey, K. I.; Somayaji, V.; Brown, R. S.
Journal of the American Chemical Society, 1989 , vol. 111, # 4 p. 1445 - 1452
反应条件
1: 52 percent / p-toluenesulfonic acid / Heating 2: 1.) n-BuLi / 1.) THF, hexane, -40 deg C, 30 min; 2.) room temp., overnight 3: H2O / 0.5 h / pH 4 4: 83 percent / NaBH4 / methanol View Scheme
参考文献
Skorey, K. I.; Somayaji, V.; Brown, R. S.
Journal of the American Chemical Society, 1989 , vol. 111, # 4 p. 1445 - 1452
反应条件
1: 1.) n-BuLi / 1.) THF, hexane, -40 deg C, 30 min; 2.) room temp., overnight 2: H2O / 0.5 h / pH 4 3: 83 percent / NaBH4 / methanol View Scheme
参考文献
Skorey, K. I.; Somayaji, V.; Brown, R. S.
Journal of the American Chemical Society, 1989 , vol. 111, # 4 p. 1445 - 1452
