(2R,3S,4S,5S)-5-羟基-2,3,4-三(苄氧基)-5-[(苄氧基)甲基]-环己酮合成路线 （共 18 条）
反应条件
nickel in 1,4-dioxane 0.5 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 57, # 13 p. 3642 - 3650
反应条件
tin(IV) chloride in dichloromethane T=-78 - -30°C; 2.5 h;
参考文献
Organic Letters, , vol. 8, # 18 p. 3935 - 3938
反应条件
1.1: AlMe3 / CH2Cl2 / 20 °C 2.1: 91 percent / triethylamine; 4-(dimethylamino)pyridine / dimethylformamide / 2 h / 20 °C 3.1: dimethyl sulfoxide; acetic anhydride / 20 °C 3.2: 80 percent / ZnCl2 / tetrahydrofuran; H2O / Heating View Scheme
参考文献
Tetrahedron, , vol. 56, # 37 p. 7109 - 7122
反应条件
cesium fluoride in acetonitrile T=0°C; 4 h; Further byproducts given;
参考文献
Organic Letters, , vol. 8, # 18 p. 3935 - 3938
反应条件
1.1: Mg; I2 / tetrahydrofuran / Heating 1.2: tetrahydrofuran / 21 h / 0 - 20 °C 2.1: 42 percent / DMSO; oxalyl chloride; Et3N / tetrahydrofuran / -78 - 0 °C 3.1: 20 percent / BF3*OEt2 / CH2Cl2 / 7 h / -78 - 20 °C View Scheme
参考文献
Organic Letters, , vol. 8, # 18 p. 3935 - 3938
反应条件
1: 1) trifluoroacetic anhydride, DMSO, 2) Et3N / 1) CH2Cl2, -75 to -65 deg C, 1 h, b) CH2Cl2, 15 min 2: 71 percent / Bu3SnH, AIBN / toluene / 1 h / 100 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 57, # 13 p. 3642 - 3650
反应条件
1: 75 percent / NaBH3CN / methanol / 16 h / Ambient temperature 2: 94 percent / 90 percent formic acid, Pd-black / methanol / Ambient temperature View Scheme
参考文献
Fukase; Horii
Journal of Organic Chemistry, 1992 , vol. 57, # 13 p. 3651 - 3658
反应条件
sodium cyanoborohydride in methanol 16 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 57, # 13 p. 3651 - 3658
