4-氯-7-{5-O-[二甲基(2-甲基-2-丙基)硅烷基]-2,3-O-异亚丙基-beta-D-来苏呋喃糖基}-7H-吡咯并[2,3-d]嘧啶-2-胺合成路线 （共 7 条）
反应条件
1: 83 percent / methanol / 8 h / Heating 2: 92 percent / aq. trifluoroacetic acid / 0.5 h / Ambient temperature View Scheme
参考文献
Seela; Soulimane; Mersmann; Jurgens
Helvetica Chimica Acta, 1990 , vol. 73, # 7 p. 1879 - 1887
反应条件
trifluoroacetic acid 1) methanol, reflux, 6 h; 2) water, 0-5 deg C, 0.5 h; Yield given. Multistep reaction;
参考文献
Ramasamy; Imamura; Robins; Revankar
Journal of Heterocyclic Chemistry, 1988 , vol. 25, # 6 p. 1893 - 1898
反应条件
methanol T=70°C; 4.5 h;
参考文献
Saito, Yoshio; Kato, Kuniki; Umezawa, Kazuo
Tetrahedron, 1998 , vol. 54, # 17 p. 4251 - 4266
反应条件
1: 2) trifluoroacetic acid / 1) methanol, reflux, 6 h; 2) water, 0-5 deg C, 0.5 h 2: 92 percent / sodium iodide, chlorotrimethylsilane / acetonitrile / 1) RT, 1 h; 2) reflux, 4 h View Scheme
参考文献
Seela; Soulimane; Mersmann; Jurgens
Helvetica Chimica Acta, 1990 , vol. 73, # 7 p. 1879 - 1887
反应条件
in methanol 8 h; Heating;
参考文献
Ramasamy; Imamura; Robins; Revankar Tetrahedron Letters, 1987 , vol. 28, # 43 p. 5107 - 5110
反应条件
Multi-step reaction with 2 steps 1: methanol / 4.5 h / Heating2: 701 g / n-Bu4NF / tetrahydrofuran / 14 h / Ambient temperature
参考文献
Saito, Yoshio; Kato, Kuniki; Umezawa, Kazuo Tetrahedron, 1998 , vol. 54, # 17 p. 4251 - 4266
反应条件
With trifluoroacetic acid 1 h; Ambient temperature;
参考文献
Seela; Soulimane; Mersmann; Jurgens Helvetica Chimica Acta, 1990 , vol. 73, # 7 p. 1879 - 1887
