7-(beta-D-来苏呋喃糖基)-4-甲氧基-7H-吡咯并[2,3-d]嘧啶-2-胺合成路线 （共 9 条）
反应条件
trifluoroacetic acid 0.5 h; Ambient temperature;
参考文献
Ramasamy; Imamura; Robins; Revankar
Tetrahedron Letters, 1987 , vol. 28, # 43 p. 5107 - 5110
反应条件
in methanol 24 h; Ambient temperature;
参考文献
Seela; Soulimane; Mersmann; Jurgens
Helvetica Chimica Acta, 1990 , vol. 73, # 7 p. 1879 - 1887
反应条件
trifluoroacetic acid 1 h; Ambient temperature;
参考文献
Seela; Soulimane; Mersmann; Jurgens
Helvetica Chimica Acta, 1990 , vol. 73, # 7 p. 1879 - 1887
反应条件
1: 83 percent / methanol / 8 h / Heating 2: 92 percent / aq. trifluoroacetic acid / 0.5 h / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 28, # 43 p. 5107 - 5110
反应条件
1: 1) KOH, tris<2-(2-methoxyethoxy)ethyl>amine / 1) MeCN, 10 min, 2) r.t., 20 h 2: 77 percent / 90percent aq. CF3COOH / 1 h / Ambient temperature 3: 76 percent / methanol / 24 h / Ambient temperature View Scheme
参考文献
Helvetica Chimica Acta, , vol. 73, # 7 p. 1879 - 1887
反应条件
1: 1) KOH, tris<2-(2-methoxyethoxy)ethyl>amine / 1) MeCN, 10 min, 2) r.t., 20 h 2: 77 percent / 90percent aq. CF3COOH / 1 h / Ambient temperature 3: 76 percent / methanol / 24 h / Ambient temperature View Scheme
参考文献
Helvetica Chimica Acta, , vol. 73, # 7 p. 1879 - 1887
反应条件
1: 1) KOH, tris<2-(2-methoxyethoxy)ethyl>amine / 1) MeCN, 10 min, 2) r.t., 20 h 2: 68 percent / 90percent aq. CF3COOH / 1 h / Ambient temperature View Scheme
参考文献
Helvetica Chimica Acta, , vol. 73, # 7 p. 1879 - 1887
反应条件
trifluoroacetic acid 1) methanol, reflux, 6 h; 2) water, 0-5 deg C, 0.5 h; Yield given. Multistep reaction;
参考文献
Journal of Heterocyclic Chemistry, , vol. 25, # 6 p. 1893 - 1898
反应条件
chloro-trimethyl-silane; sodium iodide in acetonitrile 1) RT, 1 h; 2) reflux, 4 h;
参考文献
Ramasamy; Imamura; Robins; Revankar
Journal of Heterocyclic Chemistry, 1988 , vol. 25, # 6 p. 1893 - 1898
